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一键询价Quantity size:
0.2ml
Concentration:
1mg/ml脯氨酰羟化酶抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
PHD1 catalyzes the posttranslational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins and hydroxylates HIF-1 alpha at Pro-402 and Pro-564, and HIF-2 alpha. 脯氨酰羟化酶抗体 It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex. It may play a role in cell growth regulation.
脯氨酰羟化酶抗体 Also known as:
Egl nine homolog 2; prolyl hydroxylase;EGLN 2; EGLN2; EIT 6; EIT6; HIF P4H 1; HIF PH1; HIFPH1; HPH 3; HPH3; P4H1; PHD 1; PHD1; EGL nine (C.elegans) homolog 2; EGLN2_HUMAN.
Specificity:
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Rabbit Polyclonal IgG,脯氨酰羟化酶抗体 affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Cow, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human PHD1/prolyl 脯氨酰羟化酶抗体 hydroxylase.
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Predicted Molecular Weight: 44kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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