酪酪肽抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 酪酪肽抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Peptide tyrosine tyrosine (PYY) was originally isolated from porcine gut, which exhibits striking sequence homology with members of the pancreatic polypeptide family, including neuropeptide tyrosine (NPY). The peptide is localized to enteroglucagon containing (L/EG) and pancreatic (A) cells in many mammalian and non-mammalian species. PYY gene expression is upregulated by various growth factors, including growth hormone and insulin-like growth factor and the physiological effects of PYY are mediated by G-protein (G alpha i2) coupled Y-type receptors (‘Y2 receptors of a酪酪肽抗体 PYY preferring subtype’). Various actions have been reported for PYY, including the inhibition of upper intestinal and exocrine pancreatic secretion, small intestinal water flux and as the mediator for the fat-induced ileal brake. Recently, the infusion of normal postprandial concentrations of PYY[3-36] into human volunteers has been shown to significantly decrease appetite and reduce food intake, possibly via Y2R in the arcuate nucleus. Immunohistochemical studies on mice have shown that PYY is the earliest detectable peptide in both pancreatic islets and colonic endocrine cells which suggest that PYY may be a useful marker for endocrine progenitor cells.

酪酪肽抗体PYY1-36(human):
Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2
CAS Number: 118997-30-1; Empirical Formula (Hill Notation): C194H295N55O57; Molecular Weight: 4309.75 

Also known as:

RATGHYY; GHYY; MGC19143; 酪酪肽抗体Peptide tyrosine tyrosine; peptide YY; Peptide YY like; Peptide YY precursor; PYY 1; PYY; PYY II; PYY1; PYYI; Yy; PYY_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide human Peptide YY.

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酪酪肽抗体Predicted Molecular Weight: 4.4kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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