神经细胞PAS结构域蛋白3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml神经细胞PAS结构域蛋白3抗体   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The Per-Arnt-Sim (PAS) domain is a 270 amino acid motif that mediates associations among various PAS family transcription factors. The PAS family contains neuronal specific transcription factors known as NPAS1, NPAS2 and NPAS3, which are involved the development and maintenance of learning and memory pathways. NPAS1 regulates erythropoietin expression in developing brain. NPAS2, also designated PAS 4/MOP4, associates with MOP3 to activate transcription. NPAS3, which localizes to the nucleus and is ubiquitously expressed 神经细胞PAS结构域蛋白3抗体in the adult brain, may be involved in neurogenesis and may control regulatory pathways relevant to psychotic illness and to schizophrenia. It regulates tracheal cell fates in the embryo and is necessary for the development of the posterior spiracles and the salivary gland duct. NPAS3 contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. Efficient DNA binding by NPAS2 requires dimerization with another bHLH protein.

神经细胞PAS结构域蛋白3抗体Also known as:

Basic helix loop helix PAS protein MOP6; Basic-helix-loop-helix-PAS protein MOP6; bHLHe12; Class E basic helix-loop-helix protein 12; FLJ10003; FLJ11138; FLJ11605; Member of PAS protein 6; MOP 6; MOP6; Neuronal PAS domain containing protein 3; Neuronal PAS domain protein 3; Neuronal PAS domain-containing protein 3; Neuronal PAS3; NPAS 3; NPAS3; NPAS3_HUMAN; PAS domain-containing protein 6; PASD 6; PASD6.

Specificity:

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Rabbit Polyclonal IgG,神经细胞PAS结构域蛋白3抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human NPAS3.

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Predicted Molecular Weight: 101kDa.

神经细胞PAS结构域蛋白3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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