轴突生长诱向因子G2/神经突起生长导向因子G2抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 轴突生长诱向因子G2/神经突起生长导向因子G2抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin-1, which is the mammalian homolog of UNC-6 from C. elegans, is largely expressed in the developing nervous system and in mesodermal tissues. Netrin-1 is expressed by the floor plate as either a cell associated protein or in a diffusible form, and it binds to several surface receptor 轴突生长诱向因子G2/神经突起生长导向因子G2抗体components, including deleted in colorectal cancer (DCC) and neogenin. During embryonic development, netrin-1 diffuses through the neuronal epithelium, where it forms a chemoattractant gradient that directs axonal migration to the ventral midline of the spinal cord. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin signaling is dependent on轴突生长诱向因子G2/神经突起生长导向因子G2抗体 the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins, as the cells are repelled, rather than attracted, by the netrin gradient.

轴突生长诱向因子G2/神经突起生长导向因子G2抗体Also known as:

Laminet 2; Laminet-2; Laminet2;Lmnt2; Lmnt 2; Lmnt-2; Netrin-G2; NetrinG2; NTNG1; NTNG 1; NTNG-1; NTNG2; NTNG 2; NTNG-2; NTNG2_HUMAN; bA479K20.1; LHLL9381.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Cow, Sheep, .

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Immunogen: KLH conjugated synthetic peptide derived from human Netrin G2.

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轴突生长诱向因子G2/神经突起生长导向因子G2抗体Predicted Molecular Weight: 56kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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