神经前体细胞发育下调蛋白4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml  神经前体细胞发育下调蛋白4抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes.神经前体细胞发育下调蛋白4抗体 According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable. Involved in ubiquitination of ERBB4 intracellular domain E4ICD. Involved in the budding of many viruses. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2.

神经前体细胞发育下调蛋白4抗体Also known as:

Cell proliferation-inducing gene 53 protein; E3 ubiquitin protein ligase Nedd4; E3 ubiquitin-protein ligase NEDD4; KIAA0093; NEDD 4; NEDD-4; Nedd4; NEDD4_HUMAN; Neural precursor cell expressed developmentally down regulated 4; Neural precursor cell expressed developmentally down-regulated protein 4.

Specificity:

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Rabbit Polyclonal IgG, 神经前体细胞发育下调蛋白4抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human SRD5A2.

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神经前体细胞发育下调蛋白4抗体Predicted Molecular Weight: 145kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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kl008Ra01血管生成素1(ANGPT1)多克隆抗体Polyclonal Antibody to Angiopoietin 1 (ANGPT1)

kl009Ga01血管生成素2(ANGPT2)多克隆抗体Polyclonal Antibody to Angiopoietin 2 (ANGPT2)

kl009Gu01血管生成素2(ANGPT2)多克隆抗体Polyclonal Antibody to Angiopoietin 2 (ANGPT2)

kl009Hu01血管生成素2(ANGPT2)多克隆抗体Polyclonal Antibody to Angiopoietin 2 (ANGPT2)

kl009Mu01血管生成素2(ANGPT2)多克隆抗体Polyclonal Antibody to Angiopoietin 2 (ANGPT2)

kl009Po01血管生成素2(ANGPT2)多克隆抗体Polyclonal Antibody to Angiopoietin 2 (ANGPT2)

kl009Ra01血管生成素2(ANGPT2)多克隆抗体Polyclonal Antibody to Angiopoietin 2 (ANGPT2)

kl009Rb51血管生成素2(ANGPT2)多克隆抗体Polyclonal Antibody to Angiopoietin 2 (ANGPT2)

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kl010Ga01结缔组织生长因子(CTGF)多克隆抗体Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)

kl010Hu01结缔组织生长因子(CTGF)多克隆抗体Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)

kl010Mu01结缔组织生长因子(CTGF)多克隆抗体Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)

kl010Po01结缔组织生长因子(CTGF)多克隆抗体Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)

kl010Ra01结缔组织生长因子(CTGF)多克隆抗体Polyclonal Antibody to Connective Tissue Growth Factor (CTGF)

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kl011Ca01脑源性神经营养因子(BDNF)多克隆抗体Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF)

kl011Eq01脑源性神经营养因子(BDNF)多克隆抗体Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF)

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