磷酸化丝裂原活化蛋白激酶激酶3抗体

Quantity size:

0.1ml

Concentration:

1mg/ml 磷酸化丝裂原活化蛋白激酶激酶3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is 磷酸化丝裂原活化蛋白激酶激酶3抗体necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq].

磷酸化丝裂原活化蛋白激酶激酶3抗体Also known as:

MEK3 (phospho Thr222); MEK3 (phospho T222); p-MEK3 (Thr222); p-MEK3 (T222); Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; map2k3; MAPK ERK kinase 3; MAPK/ERK kinase 3; MAPKK 3; MAPKK3; MEK 3; MEK3; Mitogen activated protein kinase kinase 3; MKK3; MP2K3_HUMAN; PRKMK3.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化丝裂原活化蛋白激酶激酶3抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Cow, Horse, Sheep, .

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human MEK3 around the phosphorylation site of Thr222.

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Predicted Molecular Weight: 39kDa.

磷酸化丝裂原活化蛋白激酶激酶3抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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