获取电话Quantity size:
0.2ml
Concentration:
1mg/ml 富含亮氨酸重复丝氨酸/苏氨酸蛋白激酶1抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. LRRK1 (leucine-rich 富含亮氨酸重复丝氨酸/苏氨酸蛋白激酶1抗体repeat serine/threonine-protein kinase 1), also known as RIPK6, Roco1 or KIAA1790, is a 2,038 amino acid cytoplasmic protein that contains one protein kinase domain, four ANK repeats and 11 leucine-rich repeats and belongs to the Ser/Thr protein kinase family. Using magnesium as a cofactor, LRRK1 catalyzes the ATP-dependent phosphorylation 富含亮氨酸重复丝氨酸/苏氨酸蛋白激酶1抗体of target proteins. The gene encoding LRRK1, which is expressed as four alternatively spliced isoforms, is thought to be involved in the pathogenesis of Parkinson's disease.
Also known as:
KIAA1790; Leucine rich repeat serine/threonine protein kinase 1; Leucine-rich repeat serine/threonine-protein kinase 1; LRRK 1; Lrrk1; LRRK1_HUMAN; RIPK6; Roco1.
富含亮氨酸重复丝氨酸/苏氨酸蛋白激酶1抗体Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human LRRK1.
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富含亮氨酸重复丝氨酸/苏氨酸蛋白激酶1抗体Predicted Molecular Weight: 225kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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