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酸敏感性钾离子通道蛋白抗体

酸敏感性钾离子通道蛋白抗体

价格: 面议

品牌:康朗生物

供货周期: 现货

货号:KL2963R

规格:0.1ml/0.2ml

Quantity size:

0.2ml

Concentration:

1mg/ml 酸敏感性钾离子通道蛋白抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, 酸敏感性钾离子通道蛋白抗体aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents. KCNK9 gene has been localized to the chromosomal region 8q24. The protein is expressed at high levels mainly in the brain and at low levels in other tissues. In contrast to normal tissues, it was found that KCNK9 is amplified in some human carcinomas such as breast, lung, colon and metastatic prostate.酸敏感性钾离子通道蛋白抗体 In 10% of breast cancer patients this gene is amplified, and in 44% the protein is over expressed. Monoclonal antibodies to KNCK9 are an important tool for studying the potassium channel family of proteins in different tissues.

酸敏感性钾离子通道蛋白抗体Also known as:

cTBAK 1; Acid sensitive potassium channel protein TASK 1; Cardiac two pore background K(+) channel; K2p3.1; OAT1; potassium channel, subfamily K, member 3; rTASK; TASK 1; TBAK1; TWIK related acid sensitive K+ channel; Two pore potassium channel KT3.1; KCNK3; TASK; TASK1; PPH4; TASK; TASK-1; TBAK1; KCNK3_HUMAN.

Specificity:

Rabbit Polyclonal IgG, affinity purified by Protein A.

Reacts with: Human, Mouse, Rat, Dog, Cow, .

Immunogen: KLH conjugated synthetic peptide derived from human KCNK3.

酸敏感性钾离子通道蛋白抗体Predicted Molecular Weight: 43kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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生化试剂 酸敏感性钾离子通道蛋白抗体由上海康朗生物科技有限公司为您提供,如想了解更多关于抗体/抗原 酸敏感性钾离子通道蛋白抗体的报价、规格、厂家等信息,欢迎来电或留言咨询。除供应酸敏感性钾离子通道蛋白抗体外,上海康朗生物科技有限公司还可为您提供: β-淀粉酶,9000-91-3、 干扰素调节因子3(IRF3)重组蛋白 、 山奈酚-3-鼠李糖苷,482-39-3
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