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一键询价Quantity size:
0.1ml
Concentration:
1mg/ml 艾滋病病毒Nef抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Nef is a early protein that appears to play a role in optimizing the host cell environment for viral replication without causing cell death by apoptosis. Nef enhances virus infectivity and 艾滋病病毒Nef抗体pathogenicity. It down modulates surface MHC I molecules and internalized molecules are sequested to the trans-Golgi network. The number of cell surface CD4 antigen are decreased by interacting with the Src family kinase LCK thereby inducing LCK CD4 dissociation and by increasing clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation.
艾滋病病毒Nef抗体Also known as:
C terminal core protein; F protein; NEF_HV1A2; Nef; Negative factor; p27.
Specificity:
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Rabbit Polyclonal IgG,艾滋病病毒Nef抗体 affinity purified by Protein A.
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Reacts with: HIV1.
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Immunogen: KLH conjugated synthetic peptide derived from human HIV1 Nef.
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Predicted Molecular Weight: 24kDa.
艾滋病病毒Nef抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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