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德国耶拿 multi N/C 3100 TOC总有机碳/总氮分析仪型号： multi N/C 3100 -
宏华仪器SHA-C数显水浴恒温振荡器型号： SHA-C -
Hitachi日立CT15RE台式离心机型号： CT15RE -
电热鼓风干燥箱型号： CS101-ABN -
Agilent GC 8890 气相色谱系统型号： 8890 GC -
贝克曼库尔特Allegra X-30R 台式冷冻离心机型号： Allegra X-30R -
Ugo Basile动态足底触觉仪,足底触觉测试仪型号： Ugo Basile动态足底触觉仪,足底触觉测试仪 -
体积式3D生物打印机型号： Tomolite -
珀金埃尔默PerkinElmer NexION 1100/1000G ICP-MS型号： NexION 1100/1000G ICP-MS
获取电话Quantity size:
0.2ml
Concentration:
1mg/ml 己糖激酶2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose-6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids.己糖激酶2抗体 Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HXK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines. HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues. Of the hexokinases,己糖激酶2抗体 HXK III has the highest affinity for glucose. Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, determining the “set point” for insulin secretion.
Also known as:
Hexokinase 2; Hexokinase 2 muscle; Hexokinase type II; Hexokinase-2; HK 2; HK II; HK2; HKII; HxK 2; HxK2; HXK2_HUMAN; Muscle form hexokinase; DKFZp686M1669.
Specificity:
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Rabbit Polyclonal IgG,己糖激酶2抗体 affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
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Immunogen: KLH conjugated synthetic peptide derived from human Hexokina.
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Predicted Molecular Weight: 101kDa.
己糖激酶2抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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