磷酸化真核翻译起始因子4E抗体

Quantity size:

0.1ml

Concentration:

1mg/ml  磷酸化真核翻译起始因子4E抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA.磷酸化真核翻译起始因子4E抗体 Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.

磷酸化真核翻译起始因子4E抗体Also known as:

eIF4E (phospho S209); p-eIF4E (phospho S209);eIF4G (phospho-Ser209); eIF4G (phospho-S209); p-eIF4G (Ser209); p-eIF4G (S209); eIF 4 gamma 1; eIF 4G 1; eIF 4G1; EIF4 gamma; EIF4F; EIF4G; EIF4GI; Eukaryotic translation initiation factor 4 gamma 1; p220; DKFZp686A1451; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; EIF4G-I; IF4G1_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, 磷酸化真核翻译起始因子4E抗体affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Daniorerio.

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Immunogen: KLH conjugated Synthesised phosphopeptide derived from human.

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Predicted Molecular Weight: 24kDa.

磷酸化真核翻译起始因子4E抗体Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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