死亡受体4抗体

Quantity size:

0.2ml

Concentration:

1mg/ml 死亡受体4抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas.死亡受体4抗体 A novel cell death receptor was recently identified and designated DR4 (for death receptor 4). The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor 1(TRAIL R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF kB activation in many tissues and cells.

死亡受体4抗体Also known as:

Apo 2; Apo2; CD 261; CD261; CD261 antigen; Cytotoxic ligand TRAIL receptor; Cytotoxic TRAIL receptor; Death receptor 4; DR 4; DR4; MGC9365; NF related apoptosis-inducing ligand receptor 1; T10A; TNF related apoptosis inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR 1;死亡受体4抗体 TRAILR1; Tumor necrosis factor receptor superfamily member 10a; Tumor necrosis factor receptor superfamily member 10A precursor; TR10A_HUMAN.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, .

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Immunogen: KLH conjugated synthetic peptide derived from human DR4.

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死亡受体4抗体Predicted Molecular Weight: 48kDa.

Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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