肌萎缩侧索硬化症相关蛋白2（2号染色体）抗体

肌萎缩侧索硬化症相关蛋白2（2号染色体）抗体Quantity size:

0.2ml

Concentration:

1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2, is connected to transferase/kinase activity and ATP binding, it has recently been shown to interact with XIAP, 肌萎缩侧索硬化症相关蛋白2（2号染色体）a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1 converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK),肌萎缩侧索硬化症相关蛋白2（2号染色体） a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.

肌萎缩侧索硬化症相关蛋白2（2号染色体）Also known as:

Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2; CALS 21; ILP interacting protein ILPIPA; ILPIP; ILPIPA; Likely ortholog of mouse polyploidy associated protein kinase; PAPK; PRO1038.

Specificity:

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Rabbit Polyclonal IgG, affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .

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Immunogen: KLH conjugated synthetic peptide derived from human ALS2CR2.

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Predicted Molecular Weight: 34kDa.

肌萎缩侧索硬化症相关蛋白2（2号染色体）Storage:

Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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