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一键询价DNA损伤关卡蛋白1抗体产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
DNA损伤关卡蛋白1抗体产品介绍
NFBD1又称MDC1(mediator of DNA damagecheckpoint protein 1)是一个参与DNA损伤细胞应答通路的重要传递和修复因子,在DNA损伤关卡、DNA损伤修复、细胞生长增殖及肿瘤发生中均有作用。
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq].
mol wt: 230kDa(human), 188kDa(mo), 147kDa(rat)
Other Aliases:
Nuclear factor with BRCT domains protein 1; DKFZp781A0122; Homologue to Drosophila photoreceptor protein calphotin; KIAA0170; MGC166888; MDC 1; Mediation of DNA damage checkpoint 1; Mediator of DNA damage checkpoint 1; Mediator of DNA Damage Checkpoint Protein 1; NFBD 1; NFBD1; Nuclear Factor with BRCT Domains Protein 1
DNA损伤关卡蛋白1抗体
hz-0963P MTNR1B/MTNR-1B(Melatonin receptor 1B) 褪黑素受体1B抗原
hz-1445P MLN(Motilin)peptide 胃动素多肽
hz-1992P mTOR(Mammalian target of rapamycin) 雷帕霉素靶蛋白
hz-1018P Muc-1/CD227 粘蛋白-1/上皮膜
hz-1047P MyD88 (myeloid differential protein-88) 髓样分化蛋白抗原
hz-2032P PMP2/FABP8(peripheral myelin protein 2) 周围神经髓鞘蛋白2抗原
hz-2166P MYSM1(Myb-like, SWIRM and MPN domain-containing protein 1) MYSM1抗原
hz-1267P MYOZ/MYOZ1(Myozenin)human、ret、mouse MYOZ抗原
hz-1049P CHRNA7(Nicotinic-Acetylcholine receptor alpha 7) 烟碱型乙酰胆碱受体α7(多肽)
hz-0829P Nanog fragment 干细胞关键蛋白(多肽)
hz-0903P Natrexone/BSA:Natrexone/KLH 纳曲酮偶联牛血清白蛋白:纳曲酮偶联血蓝蛋白
hz-1052P NAP1 (nucleosome asshzbly protein 1) 核小体组装蛋白1(多肽)
hz-1172P N-cadherin N-钙粘附分子抗原
hz-1519P E-cadherin E-钙粘附分子抗原
hz-0513P Nephrin Protein 去氧肾上腺素
hz-1055P Neurocan 神经粘蛋白抗原
hz-1366P NF2/merlin(neurofibromatosis type 2) 2型神经纤维瘤抗原
hz-1417P NFATc1 活化T细胞核因子1蛋白
hz-0982P phospho-NFKB p65 (pSer536) peptide 磷酸化细胞核因子/磷酸化k基因结合核因子抗原
hz-1194P NF-KapBp50(p50 NF-kappa B;p50NFKB) 细胞核因子50/κ基因结合核因子50抗原
hz-0922P NGN3(neurogenin 3; Neurog3) 神经元素3抗原
hz-1065P NGX6 (nasopharyngeal carcinoma/NPC associated gene 6) 鼻咽癌细胞相关基因6(多肽)
hz-2012P NIT2 (nitrilase family, mhzber 2) NIT2蛋白抗原
hz-0069P NKA(Neurokinin A) 神经激肽A抗原
hz-2411P NKG2A/CD159a/KLRC1 NK细胞受体2A/自然杀伤细胞活化性受体2A抗原
hz-0938P NKG2D(natural killer cell group 2D) NK细胞受体/自然杀伤细胞活化性受体
hz-0688P Nm23(NDP Kinase A,NDPKA) 肿瘤转移抑制基因抗原
hz-1066P Nm23-H1 (nucleoside dIPhosphatase kinase A) 肿瘤抑制基因抗原
hz-1315P Nogo-B/A 轴索过度生长抑制因子-B/A抗原
hz-2072P NOS-2 peptide 一氧化氮合成酶-2多肽抗原
hz-1335P Notch1/MOTC(Neurogenic locus notch homolog protein 1) 跨膜受体蛋白Notch-1抗原
hz-1537P NADPH peptide 还原型辅酶Ⅱ抗原
hz-1069P proCNP/NPPC (pro-natriuretic peptide) 促尿钠排泄肽前体C抗原
hz-0937P NPY2R(Neuropeptide Y Receptor Type 2) 神经肽Y受体2(多肽)
hz-1070P NPY1R (neuropeptide Y1 receptor) 神经肽Y1受体抗原
hz-2184P NQO1(NAD(P)H:quinone oxidoreductase l) 醌氧化还原酶抗原