获取电话3,3'-亚甲基二吲哚
≥98%(HPLC)
Product Name: 3,3′-Diindolylmethane
| 别名: | 二(3,3'-吲哚基)甲烷;3,3'-二吲哚甲烷;DIM |
| CAS号: | 1968-05-4 |
| 分子式: | C17H14N2 |
| 分子量: | 246.31 |
| MDL号: | MFCD00195766 |
3,3'-亚甲基二吲哚
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| 介绍: | 3,3'-Diindolylmethane is an anticancer and antineoplastic agent. 3,3'-Diindolylmethane induces apoptosis in human cancer cells. 3,3'-Diindolylmethane is also an activator of CYP (cytochrome P450) and Chk2 (checkpoint kinase 2) as well as a partial agonist of aryl hydrocarbon receptor (Ah Receptor). The compound is a dimer of indole-3-carbinol. |
| 用途: | An antineoplastic agent that activates Chk 2 and cytochrome p450 |
| 熔点: | 165.0-171.0°C |
| 贮存: | 储存温度 2-8°C |
| 生化和生理学机理: | Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol.It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells.DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor.The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system. |
3,3'-亚甲基二吲哚
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