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获取电话英文名称 RASSF4
中文名称 Ras相关区域家族蛋白4抗体
别 名 AD037; Ras association (RalGDS/AF 6) domain family 4; Ras association domain family 4; Ras association (RalGDS/AF 6) domain family member 4; Ras association domain containing protein 4; RASSF 4; Tumor suppressor RASSF4; RASF4_HUMAN.
Ras相关区域家族蛋白4抗体
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 免疫学 信号转导 细胞周期蛋白 G蛋白偶联受体
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASSF4
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Ras相关区域家族蛋白4抗体 产品介绍 background:
The function of RASSF4 has not yet been determined but it may involve a role in tumor suppression. RASSF4 may act as a KRAS effector protein and may promote apoptosis and cell cycle arrest. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described.
Function:
Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Subunit:
Interacts directly with activated KRAS in a GTP-dependent manner.
Tissue Specificity:
Widely expressed. Frequently down-regulated in tumor cell lines.
Similarity:
Contains 1 Ras-associating domain.
Contains 1 SARAH domain.
Database links:
UniProtKB/Swiss-Prot: Q9H2L5.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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