获取电话英文名称 SART2
中文名称 T淋巴细胞识别鳞状细胞癌抗原2抗体
别 名 Chondroitin glucuronate 5 epimerase; Chondroitin-glucuronate 5-epimerase; Dermatan sulfate epimerase; Dermatan-sulfate epimerase; DS epimerase; DSE; DSE_HUMAN; DSEPI; OTTHUMP00000040406; SART 2; SART-2; Squamous cell carcinoma antigen recognized by T cells 2; Squamous cell carcinoma antigen recognized by T-cells 2.
T淋巴细胞识别鳞状细胞癌抗原2抗体
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 细胞类型标志物
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 110kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SART2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
T淋巴细胞识别鳞状细胞癌抗原2抗体 产品介绍 background:
The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues.
Subcellular Location:
Membrane.
Tissue Specificity:
Ubiquitously expressed with higher expression in kidney and ovary and lower expression in brain, colon and thymus. Also expressed in renal cell carcinomas, brain tumors, and in a part of melanomas and adenocarcinomas from organs other than the breast. Expressed in squamous cell carcinomas (SCC), glioma, and some adenocarcinoma cell lines, but not in breast cancer cell lines or any normal tissues (at protein level).
Similarity:
Belongs to the dermatan-sulfate isomerase family.
Database links:
Entrez Gene: 514028 Cow
Entrez Gene: 29940 Human
Entrez Gene: 212898 Mouse
Omim: 605942 Human
SwissProt: P0C2H4 Cow
SwissProt: Q9UL01 Human
SwissProt: Q8BLI4 Mouse
Unigene: 741354 Human
Unigene: 34557 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
T淋巴细胞识别鳞状细胞癌抗原2抗体
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