获取电话英文名称 SCIN
中文名称 肌切蛋白抗体
别 名 Adseverin; KIAA1905; ADSV_HUMAN; Scinderin.
肌切蛋白抗体
说 明 书 0.2ml
研究领域 细胞生物 信号转导 细胞骨架
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCIN
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
肌切蛋白抗体 产品介绍 background:
SCIN (Scinderin) is a Ca(2+) dependent actin filament severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro SCIN also has barbed end capping and nucleating activities in the presence of Ca(2+).
Function:
Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).
Subcellular Location:
Cytoplasmic, cytoskeleton.
Similarity:
Belongs to the villin/gelsolin family.
Contains 6 gelsolin-like repeats.
Gene ID:
85477
Database links:
Entrez Gene: 85477 Human
Omim: 613416 Human
SwissProt: Q9Y6U3 Human
SwissProt: D4A2G2 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌切蛋白抗体
hz-7534R PGC1 beta 过氧化物酶体增殖物激活受体γ辅激活子1β抗体
hz-7535R PGC1 alpha + beta 过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体
hz-7536R SERPINA12/Vaspin 内脏脂肪组织源性丝氨酸蛋白酶抑制蛋白抗体
hz-7537R SIRT4/SIR 2 like protein 4 沉默调节相关蛋白4抗体
hz-7538R TRIB3/p65 interacting inhibitor of NF-kappaB 神经细胞死亡诱导蛋白激酶抗体
hz-7539R SERCA1 ATPase 肌浆/内质网钙ATP酶1抗体
hz-7540R GRK5 G蛋白偶联受体激酶5抗体
hz-7541R EDG3 内皮分化型G蛋白偶联受体3抗体
hz-7551R TNFAIP3 interacting protein 3/ABIN3 肿瘤坏死因子α诱导相互作用蛋白3抗体
hz-7542R RISC/Serine carboxypeptidase 1 丝氨酸羧肽酶1抗体
hz-2731R APS APS抗体
hz-7544R SOAT1/ACAT1 胆固醇酰基转移酶1抗体
hz-3003R phospho-APS(Ser598) 磷酸化APS抗体
hz-7545R Scavenger Receptor BII 清道夫受体B2抗体
hz-7546R CD239 B细胞粘附分子CD239抗体
hz-3569R AP2 alpha 转录激活蛋白2α抗体
hz-7547R CPB2/Carboxypeptidase B2 胰羧肽酶B2抗体
hz-7548R Fibrinopeptide A 纤维蛋白肽A/血纤肽抗体
hz-7549R GAS 6 生长停滞特异性蛋白6抗体
hz-7550R AUP1/Ancient ubiquitous protein 1 原始广泛存在蛋白1抗体
hz-7552R Biglycan 骨/软骨蛋白多糖1抗体
hz-2532R ALT1 谷丙氨酸氨基转移酶1抗体
hz-7553R Eph receptor A2+A3+A4 内皮细胞受体蛋白酪氨酸激酶A2+A3+A4抗体
hz-7554R phospho-Eph receptor A2+A3+A4 (Tyr588 + Tyr596) 磷酸化内皮细胞受体蛋白酪氨酸激酶A2+A3+A4抗体
hz-7555R phospho-EPH A3+A4+A5 ( Tyr779) 磷酸化内皮细胞受体蛋白酪氨酸激酶A3+A4+A5抗体
hz-7556R FLAP/5-lipoxygenase activating protein 5脂氧合酶激活蛋白抗体
hz-7557R IKK alpha + IKK beta KB抑制蛋白激酶α/β抗体
hz-7558R MC3 Receptor 黑素皮质素受体3抗体
hz-7559R PDGF AB+BB 血小板源性生长因子AB+BB抗体
hz-7560R CPLA2 胞浆型磷脂酶A2抗体
hz-7561R TIRAP 白细胞介素1受体衔接蛋白抗体
hz-7562R phospho-TIRAP(Tyr86) 磷酸化白细胞介素1受体衔接蛋白抗体
hz-7563R TNIP2/ABIN2/TNFAIP3 interacting protein 2 肿瘤坏死因子α诱导蛋白3相互作用蛋白2抗体
hz-7564R Azurocidin/Cationic antimicrobial protein 37 肝素结合蛋白/阳离子抗菌蛋白37/天青杀素抗体
hz-7565R AGPB/Alpha 1 acid glycoprotein 2 α1酸性糖蛋白2抗体（类粘蛋白2）
hz-7566R RHBDD3 垂体瘤细胞凋亡抗体
hz-7567R RIP1 受体相互作用蛋白激酶1抗体