丝氨酸/苏氨酸SRP40抗体

英文名称    SFRS5    

中文名称    丝氨酸/苏氨酸SRP40抗体    

别    名    Delayed early protein HRS; HRS; Pre mRNA splicing factor SRP40; SFRS 5; Splicing factor arginine/serine rich 5; SRP 40; SRP40.    

丝氨酸/苏氨酸SRP40抗体        

说 明 书    0.2ml      

研究领域    细胞生物  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    39kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SFRS5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

丝氨酸/苏氨酸SRP40抗体产品介绍    background:
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2010]

Function:
SFRS5 plays a role in constitutive splicing and can modulate the selection of alternative splice sites. It is found in a pre-mRNA splicing complex with SFRS4, SNRP70, SNRPA1, SRRM1 and SRRM2. There are four isoforms.

Subcellular Location:
Nuclear

Database links:

Entrez Gene: 6430 Human

Omim: 600914 Human

SwissProt: Q13243 Human

Unigene: 706773 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

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