获取电话英文名称 TRAK1
中文名称 驱动蛋白结合蛋白1抗体
别 名 106 kDa O-GlcNAc transferase-interacting protein; 106 kDa O GlcNAc transferase interacting protein; KIAA1042; OGT(O Glc NAc transferase) interacting protein 106 KDa; OIP106; TRAK1_HUMAN; Trafficking kinesin binding protein 1; Trafficking kinesin-binding protein 1; Trafficking protein kinesin binding 1; TRAK 1.
驱动蛋白结合蛋白1抗体
说 明 书 0.2ml
研究领域 肿瘤 免疫学 信号转导 细胞骨架 肿瘤细胞生物标志物 线粒体
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 106kDa
细胞定位 细胞核 细胞浆 线粒体
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRAK1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
驱动蛋白结合蛋白1抗体 产品介绍 background:
The specific function of TRAK1 remains unknown. It interacts with O-GlcNAc transferase, RHOT1/Miro-1 and RHOT2/Miro-2. It shows high expression in spinal cord and moderate expression in all other tissues and specific brain regions examined.
Function:
Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors.
Subunit:
Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2. Interacts with HGS. Interacts with GABRA1. Interacts with KIF5C.
Subcellular Location:
Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome.
Tissue Specificity:
High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.
Post-translational modifications:
O-glycosylated.
Similarity:
Contains 1 HAP1 N-terminal domain.
Gene ID:
22906
Database links:
Entrez Gene: 22906 Human
Omim: 608112 Human
SwissProt: Q9UPV9 Human
Unigene: 535711 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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