膜型丝氨酸蛋白酶2抗体

英文名称    TMPRSS4    

中文名称    膜型丝氨酸蛋白酶2抗体    

别    名    MT SP2; Membrane type serine protease 2; TMPRSS 4; TMPRSS3; Transmembrane protease, serine 4; Transmembrane serine protease 3; UNQ776/PRO1570; TMPS4_HUMAN.    

膜型丝氨酸蛋白酶2抗体        

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  神经生物学  信号转导  肿瘤细胞生物标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    48kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human TMPRSS4 (84-130aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

膜型丝氨酸蛋白酶2抗体产品介绍    background:
TMPRSS4 is a member of the peptidase S1 family and contains 1 LDL receptor class A domain, 1 peptidase S1 domain and 1 SRCR domain. It is a probable membrane protease capable of activating ENaC and may process sodium channels in endothelial cells. TMPRSS4 is overexpressed in thyroid neoplasms, and splice variants in TMPRSS4 are thought to be linked with different cancers. Three named isoforms are produced by alternative splicing.

Function:
Probable protease. Seems to be capable of activating ENaC.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).

Tissue Specificity:
High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.

Similarity:
Belongs to the peptidase S1 family. 
Contains 1 LDL-receptor class A domain. 
Contains 1 peptidase S1 domain. 
Contains 1 SRCR domain.

Gene ID:
56649

Database links:

Entrez Gene: 451581 Chimpanzee

Entrez Gene: 489387 Dog

Entrez Gene: 101147411 Gorilla

Entrez Gene: 100071190 Horse

Entrez Gene: 56649 Human

Entrez Gene: 100390415 Marmoset (common)

Entrez Gene: 100436934 Orangutan

Omim: 606565 Human

SwissProt: Q9NRS4 Human

Unigene: 161985 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

膜型丝氨酸蛋白酶2抗体

hz-6718R Dystrophin/DMD  肌营养不良蛋白

hz-6719R LGI1/ETL1  富含亮氨酸胶质瘤失活蛋白1抗体

hz-6720R GANAB/alpha Glucosidase II  α葡萄糖苷酶2抗体

hz-6721R NLG1/KIRREL2  肾病样蛋白1抗体

hz-6722R MAPK organizer 1/Morg1  丝裂原活化蛋白激酶组织蛋白1抗体

hz-6723R PNPLA6/NTE  含patatin样磷脂酶6抗体

hz-6724R OTC  鸟氨酸氨基甲酰转移酶抗体

hz-6725R Desmoglein 1/DSG1  桥粒芯糖蛋白1

hz-6727R CAMKIV/CAMK4  钙/钙调蛋白依赖性蛋白激酶4抗体

hz-6728R phospho-CAMK4(Thr196 + Thr200)  磷酸化钙/钙调蛋白依赖性蛋白激酶4抗体

hz-6730R LBP1/Upstream Binding Protein 1  上游结合蛋白1抗体

hz-6732R SDF4  基质细胞衍生因子4抗体（钙结合蛋白）

hz-6733R SECTM1  分泌和跨膜蛋白1抗体

hz-6734R SERBP1  纤溶酶原激活物抑制剂1 RNA结合蛋白抗体

hz-6735R SFR19  剪接因子，精氨酸/丝氨酸丰富19

hz-6736R SOX11  转录因子SOX-11蛋白抗体

hz-6737R SVH/ARMC10  肝癌蛋白剪接变异体蛋白抗体

hz-6738R THRSP  甲状腺激素反应蛋白抗体

hz-6739R TIMM17A  线粒体内膜转位酶抗体

hz-6740R TMhz49  跨膜蛋白49抗体

hz-6741R TMS1/ASC  凋亡相关斑点样蛋白ASC抗体

hz-6742R TPD52/Prostate and colon associated protein  前列腺癌和结肠癌相关蛋白

hz-6743R TPD54/TPD52L2  肿瘤蛋白D54蛋白抗体

hz-6744R TRIM47  星形细胞瘤高表达蛋白抗体（环指蛋白100）

hz-6745R TSP50  肿瘤/睾丸抗原20抗体

hz-6746R TULP2/CT65/Cancer testis antigen 65  肿瘤/睾丸抗原65

hz-6747R TERT/EST2/Telomerase reverse transcriptase  端粒酶相关蛋白2抗体（端粒酶逆转录酶）

hz-6748R UBAP1  泛素相关蛋白1抗体（鼻咽癌相关基因20蛋白）

hz-6749R UXT/Ubiquitously expressed transcript  广泛表达转录蛋白UXT抗体

hz-6750R WDR16  WD重复蛋白16抗体

hz-6751R WDR19  WD重复膜蛋白19抗体

hz-6752R WSB2/WD SOCS box protein 2  信号传导抑制蛋白WD重复蛋白2抗体

hz-6753R WWP1  WW结构域E3泛素连接酶1抗体

hz-6754R YY1AP1/HCCA2  肝癌相关蛋白2抗体（转录因子YY1结合蛋白1抗体）

hz-6755R ZNF146  锌指蛋白146抗体

hz-6756R ZNF23  锌指蛋白23抗体

hz-6757R ZNF364/BCA2/RNF115  乳腺癌相关基因2抗体（锌指蛋白364）

hz-6758R FAM89B/MMTV-R  乳腺肿瘤病毒受体同源蛋白抗体