TRK融合基因蛋白抗体

英文名称    TRK fused gene    

中文名称    TRK融合基因蛋白抗体    

别    名    TRK-T3; TRK fused gene; FLJ36137; HMSNP; OTTHUMP00000214045; OTTHUMP00000214046; OTTHUMP00000214047; OTTHUMP00000214048; Protein TFG; SPG57; TF6; TFG; TFG_HUMAN; TRK fused; TRK fused gene; TRK fused gene protein; TRK-fused gene protein; TRKT3; TRKT3 oncogene.    

TRK融合基因蛋白抗体        

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  信号转导  细胞凋亡  淋巴细胞  b-淋巴细胞  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    43kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human TRK fused gene    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

TRK融合基因蛋白抗体产品介绍    background:
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]

Tissue Specificity:
Ubiquitous.

DISEASE:
Defects in TFG are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TFG is found in thyroid papillary carcinomas. Translocation t(1;3)(q21;q11) with NTRK1. The TFG sequence is fused to the 3'-end of NTRK1 generating the TRKT3 (TRK-T3) fusion transcript.

Gene ID:
10342

Database links:

Entrez Gene: 10342 Human

Entrez Gene: 21787 Mouse

Entrez Gene: 360709 Rat

Omim: 602498 Human

SwissProt: Q92734 Human

Unigene: 518123 Human

Unigene: 425970 Mouse

Unigene: 24822 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

TRK融合基因蛋白抗体

hzf-0368P Mouse IgM/FITC  荧光素标记小鼠IgM

hzF-0309P pig IgG/FITC  荧光素标记猪IgG

hzf-0777P Mink IgG/FITC  荧光素标记水貂IgG

hzF-0295P Rabbit IgG/FITC  荧光素FITC标记兔IgG(细胞流式同型对照)

hzf-0369P Rabbit IgM/FITC  荧光素标记兔IgM

hzF-0293P Rat IgG/FITC  荧光素FITC标记大鼠IgG(细胞流式同型对照)

hzf-0346P Rat IgM/FITC  荧光素标记大鼠IgM

hzF-0884P rHIL-1Ra/FITC  荧光素标记重组人白介素-1受体拮抗剂

hzF-P0002 KLH/FITC  荧光素标记血蓝蛋白

hzF-0945P HSA(Human sermu albumin)/FITC  荧光素标记人血白蛋白

hzF-P0003 OVA/FITC  荧光素标记鸡卵白蛋白

hzF-2179P AACT/FITC  荧光素标记胰糜蛋白酶

七、正常动物血清及免疫球蛋白

编  号 名  称

hz-0292P-hzy3 BSA/Cy3  荧光素Cy3标记牛血清白蛋白

hz-0366R-hzy3 Rb Anti-FITC/Cy3  荧光素Cy3标记兔抗FITC

hz-0295P-A350 Rabbit IgG/Alexa Fluor 350  Alexa Fluor 350标记兔IgG(细胞流式同型对照)

hz-0296P-A350 Mouse IgG/Alexa Fluor 350  Alexa Fluor 350标记小鼠IgG(细胞流式同型对照)

hz-0295P-PE-hzy3 Rabbit IgG/PE-Cy3  荧光素PE-Cy3标记兔IgG(细胞流式同型对照)

hz-0296P-PE-hzy3 Mouse IgG/PE-Cy3  荧光素PE-Cy3标记小鼠IgG(细胞流式同型对照)

hz-0294P-PE-hzy3 Goat IgG/PE-Cy3  荧光素PE-Cy3标记羊IgG(细胞流式同型对照)

hz-0360G-hzy3 Goat Anti-human IgA/Cy3  荧光素Cy3标记羊抗人IgA

hz-0294P-A350 Goat IgG/Alexa Fluor 350  Alexa Fluor 350标记羊IgG(细胞流式同型对照)

hz-0293P-A350 Rat IgG/Alexa Fluor 350  Alexa Fluor 350标记大鼠IgG(细胞流式同型对照)

hz-0292P-A488 BSA/Alexa Fluor 488  Alexa Fluor 488标记牛血清白蛋白

hzb-0292P BSA/BIOTIN  生物素标记牛血清白蛋白

hz-0360G-A488 Goat Anti-human IgA/Alexa Fluor 488  Alexa Fluor 488标记羊抗人IgA

hz-0295P-hzy5 Rabbit IgG/Cy5  荧光素Cy5.5标记兔IgG(细胞流式同型对照)

hz-0295P-A488 Rabbit IgG/Alexa Fluor 488  Alexa Fluor 488标记兔IgG(细胞流式同型对照)

hz-0296P-A488 Mouse IgG/Alexa Fluor 488  Alexa Fluor 488标记小鼠IgG(细胞流式同型对照)

hz-0294P-A488 Goat IgG/Alexa Fluor 488  Alexa Fluor 488标记羊IgG(细胞流式同型对照)

hz-0293P-A488 Rat IgG/Alexa Fluor 488  Alexa Fluor 488标记大鼠IgG(细胞流式同型对照)

hz-0292P-hzy5.5 BSA/Cy5.5  荧光素Cy5.5标记牛血清白蛋白

hz-0295P-hzy5.5 Rabbit IgG/Cy5.5  荧光素Cy5.5标记兔IgG(细胞流式同型对照)

hz-0296P-hzy5.5 Mouse IgG/Cy5.5  荧光素Cy5.5标记小鼠IgG(细胞流式同型对照)

hz-0294P-hzy5.5 Goat IgG/Cy5.5  荧光素Cy5.5标记羊IgG(细胞流式同型对照)

hz-0293P-hzy5.5 Rat IgG/Cy5.5  荧光素Cy5.5标记大鼠IgG(细胞流式同型对照)

hz-0326P Bovine IgG   (亲和纯化) 牛IgG

hz-0327P Bovine IgM  (亲和纯化) 牛IgM

hz-0310P Chicken IgG  (HPLC纯化) 鸡IgG

hz-0314P Chicken IgM  (亲和纯化) 鸡IgM