获取电话英文名称 Phosphor-UBE2s(Thr152)
中文名称 磷酸化泛素交联酶抗体
别 名 UBE2s(Phosphor T152); Phosphor-UBE2s(T152); E2 EPF; E2EPF; EPF5; UBE2S; Ubiquitin carrier protein S; Ubiquitin conjugating enzyme E2 24 kD; Ubiquitin conjugating enzyme E2S; Ubiquitin protein ligase S; AA409170; MGC101982; UBE2S_HUMAN.
磷酸化泛素交联酶抗体
说 明 书 0.1ml
产品类型 磷酸化抗体
研究领域 免疫学 转录调节因子
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human UBE2s around the phosphorylation site of Thr152
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
磷酸化泛素交联酶抗体 产品介绍 background:
This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins. [provided by RefSeq, Jul 2008]
Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination.
Subunit:
Component of the APC/C complex. Interacts with CDC20, FZR1/CDH1 and VHL.
Post-translational modifications:
Autoubiquitinated by the APC/C complex during G1, leading to its degradation by the proteasome.
Similarity:
Belongs to the ubiquitin-conjugating enzyme family.
Gene ID:
27338
Database links:
Entrez Gene: 617703 Cow
Entrez Gene: 27338 Human
Entrez Gene: 77891 Mouse
Entrez Gene: 292588 Rat
GenBank: NP_055316.2 Human
Omim: 610309 Human
SwissProt: Q1RML1 Cow
SwissProt: Q16763 Human
SwissProt: Q921J4 Mouse
SwissProt: B5DFI8 Rat
Unigene: 396393 Human
Unigene: 389787 Mouse
Unigene: 120398 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化泛素交联酶抗体
hz-0377R-AF555 Rabbit Anti-mouse IgG-Fc/Alexa Fluor 555 Alexa Fluor 555标记的兔抗小鼠IgG-Fc
hz-0377R-AF647 Rabbit Anti-mouse IgG-Fc/Alexa Fluor 647 Alexa Fluor 647标记的兔抗小鼠IgG-Fc
hz-0377R-PE-hzy5.5 Rabbit Anti-mouse IgG-Fc/PE-Cy5.5 PE-Cy5.5标记的兔抗小鼠IgG-Fc
hz-0377R-PE-hzy7 Rabbit Anti-mouse IgG-Fc/PE-Cy7 PE-Cy7标记的兔抗小鼠IgG-Fc
hz-0377R-AP Rabbit Anti-mouse IgG-Fc/AP 碱性磷酸酶（AP）标记的兔抗小鼠IgG-Fc
hz-0377R-Gold Rabbit Anti-mouse IgG-Fc/Gold 胶体金标记的兔抗小鼠IgG-Fc
hz-0377R-hzy3 Rabbit Anti-mouse IgG-Fc/Cy3 Cy3标记的兔抗小鼠IgG-Fc
hz-0377R-hzy5 Rabbit Anti-mouse IgG-Fc/Cy5 Cy5标记的兔抗小鼠IgG-Fc
hz-0377R-hzy5.5 Rabbit Anti-mouse IgG-Fc/Cy5.5 Cy5.5标记的兔抗小鼠IgG-Fc
hz-0377R-hzy7 Rabbit Anti-mouse IgG-Fc/Cy7 Cy7标记的兔抗小鼠IgG-Fc
hz-0377R-PE Rabbit Anti-mouse IgG-Fc/PE PE标记的兔抗小鼠IgG-Fc
hz-0377R-FIThz Rabbit Anti-mouse IgG-Fc/FITC FITC标记的兔抗小鼠IgG-Fc
hz-0377R-RBIThz Rabbit Anti-mouse IgG-Fc/RBITC 罗丹明标记的兔抗小鼠IgG-Fc
hz-0377R-Bio Rabbit Anti-mouse IgG-Fc/Bio 生物素标记的兔抗小鼠IgG-Fc
hz-0335R-RBIThz Rabbit Anti-Monkey IgG/RBITC 罗丹明标记的兔抗猴IgG
hz-0335R-FIThz Rabbit Anti-Monkey IgG/FITC FITC标记的兔抗猴IgG
hz-0335R-HRP Rabbit Anti-Monkey IgG/HRP 辣根过氧化物酶标记的兔抗猴IgG
hz-0335R-Gold Rabbit Anti-Monkey IgG/Gold 胶体金标记的兔抗猴IgG
hz-0335R-AP Rabbit Anti-Monkey IgG/AP 碱性磷酸酶（AP）标记的兔抗猴IgG
hz-0335R-Bio Rabbit Anti-Monkey IgG/Bio 生物素标记的兔抗猴IgG
hz-0335R-hzy3 Rabbit Anti-Monkey IgG/Cy3 Cy3标记的兔抗猴IgG
hz-0335R-hzy5 Rabbit Anti-Monkey IgG/Cy5 Cy5标记的兔抗猴IgG
hz-0335R-hzy5.5 Rabbit Anti-Monkey IgG/Cy5.5 Cy5.5标记的兔抗猴IgG
hz-0335R-hzy7 Rabbit Anti-Monkey IgG/Cy7 Cy7标记的兔抗猴IgG
hz-0335R-PE Rabbit Anti-Monkey IgG/PE PE标记的兔抗猴IgG
hz-0335R-PE-hzy3 Rabbit Anti-Monkey IgG/PE-Cy3 PE-Cy3标记的兔抗猴IgG
hz-0335R-PE-hzY5 Rabbit Anti-Monkey IgG/PE-CY5 PE-CY5标记的兔抗猴IgG
hz-0335R-APhz Rabbit Anti-Monkey IgG/APC APC标记的兔抗猴IgG
hz-0335R-AF350 Rabbit Anti-Monkey IgG/Alexa Fluor 350 Alexa Fluor 350标记的兔抗猴IgG
hz-0335R-AF488 Rabbit Anti-Monkey IgG/Alexa Fluor 488 Alexa Fluor 488标记的兔抗猴IgG
hz-0335R-AF555 Rabbit Anti-Monkey IgG/Alexa Fluor 555 Alexa Fluor 555标记的兔抗猴IgG
hz-0335R-AF647 Rabbit Anti-Monkey IgG/Alexa Fluor 647 Alexa Fluor 647标记的兔抗猴IgG
hz-0335R-PE-hzy5.5 Rabbit Anti-Monkey IgG/PE-Cy5.5 PE-Cy5.5标记的兔抗猴IgG