获取电话英文名称 Vesicular Acetylcholine Transporter
中文名称 囊泡乙酰胆碱通道抗体
别 名 Vesicular Acetylcholine Transporter; MGC12716; rVAT; SLC18A3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; VACht; VAChT; VACHT_HUMAN.
囊泡乙酰胆碱通道抗体
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 心血管 细胞生物 免疫学 神经生物学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human VAT
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
囊泡乙酰胆碱通道抗体产品介绍 background:
Vesicular Acetylcholine Transporter (VAChT), (~70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate.
VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders.
Function:
Involved in acetylcholine transport into synaptic vesicles.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Peripheral and central cholinergic nervous systems.
Similarity:
Belongs to the major facilitator superfamily.
Vesicular transporter family.
Gene ID:
6572
Database links:
Entrez Gene: 6572 Human
Entrez Gene: 20508 Mouse
Entrez Gene: 60422 Rat
Omim: 600336 Human
SwissProt: Q16572 Human
SwissProt: O35304 Mouse
SwissProt: Q62666 Rat
Unigene: 654374 Human
Unigene: 190503 Mouse
Unigene: 9987 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
囊泡乙酰胆碱通道抗体
hz-0310G-FIThz Goat Anti-Chicken IgG/FITC FITC标记的羊抗鸡IgG
hz-0310G-hzy3 Goat Anti-Chicken IgG/Cy3 Cy3标记的羊抗鸡IgG
hz-0310G-hzy5 Goat Anti-Chicken IgG/Cy5 Cy5标记的羊抗鸡IgG
hz-0310G-hzy5.5 Goat Anti-Chicken IgG/Cy5.5 Cy5.5标记的羊抗鸡IgG
hz-0310G-hzy7 Goat Anti-Chicken IgG/Cy7 Cy7标记的羊抗鸡IgG
hz-0310G-PE Goat Anti-Chicken IgG/PE PE标记的羊抗鸡IgG
hz-0310G-PE-hzy3 Goat Anti-Chicken IgG/PE-Cy3 PE-Cy3标记的羊抗鸡IgG
hz-0310G-PE-hzY5 Goat Anti-Chicken IgG/PE-CY5 PE-CY5标记的羊抗鸡IgG
hz-0310G-APhz Goat Anti-Chicken IgG/APC APC标记的羊抗鸡IgG
hz-0310G-AF350 Goat Anti-Chicken IgG/Alexa Fluor 350 Alexa Fluor 350标记的羊抗鸡IgG
hz-0310G-AF488 Goat Anti-Chicken IgG/Alexa Fluor 488 Alexa Fluor 488标记的羊抗鸡IgG
hz-0310G-AF555 Goat Anti-Chicken IgG/Alexa Fluor 555 Alexa Fluor 555标记的羊抗鸡IgG
hz-0310G-AF647 Goat Anti-Chicken IgG/Alexa Fluor 647 Alexa Fluor 647标记的羊抗鸡IgG
hz-0310G-PE-hzy5.5 Goat Anti-Chicken IgG/PE-Cy5.5 PE-Cy5.5标记的羊抗鸡IgG
hz-0310G-PE-hzy7 Goat Anti-Chicken IgG/PE-Cy7 PE-Cy7标记的羊抗鸡IgG
hz-0310G-Bio Goat Anti-Chicken IgG/Bio 生物素标记的羊抗鸡IgG
hz-0310G-AP Goat Anti-Chicken IgG/AP 碱性磷酸酶（AP）标记的羊抗鸡IgG
hz-0310G-HRP Goat Anti-Chicken IgG/HRP 辣根过氧化物酶标记的羊抗鸡IgG
hz-0297G-HRP Goat Anti-human IgG/HRP 辣根过氧化物酶标记的羊抗人IgG
hz-0297G-AP Goat Anti-human IgG/AP 碱性磷酸酶（AP）标记的羊抗人IgG
hz-0297G-PE-hzY5 Goat Anti-human IgG/PE-CY5 PE-CY5标记的羊抗人IgG
hz-0297G-hzy3 Goat Anti-human IgG/Cy3 Cy3标记的羊抗人IgG
hz-0297G-hzy5 Goat Anti-human IgG/Cy5 Cy5标记的羊抗人IgG
hz-0297G-hzy5.5 Goat Anti-human IgG/Cy5.5 Cy5.5标记的羊抗人IgG
hz-0297G-PE-hzy3 Goat Anti-human IgG/PE-Cy3 PE-Cy3标记的羊抗人IgG
hz-0297G-Bio Goat Anti-human IgG/Bio 生物素标记的羊抗人IgG
hz-0297G-APhz Goat Anti-human IgG/APC APC标记的羊抗人IgG
hz-0297G-AF350 Goat Anti-human IgG/Alexa Fluor 350 Alexa Fluor 350标记的羊抗人IgG
hz-0297G-AF488 Goat Anti-human IgG/Alexa Fluor 488 Alexa Fluor 488标记的羊抗人IgG
hz-0297G-AF555 Goat Anti-human IgG/Alexa Fluor 555 Alexa Fluor 555标记的羊抗人IgG