获取电话英文名称 VPS18
中文名称 空泡分选蛋白18抗体
别 名 vacuolar protein sorting protein 18; PEP3; VPS18; KIAA1475; hVPS18; Vacuolar protein sorting 18; Vacuolar protein sorting-associated protein 18; vps18; VPS18_HUMAN.
空泡分选蛋白18抗体
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 免疫学 发育生物学 细胞周期蛋白
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 107kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human VPS18
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
空泡分选蛋白18抗体产品介绍 background:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
Subunit:
Interacts with HOOK1. Part of a large heterooligomeric complex together with VPS11, VPS16 and VPS33A. Interacts with STX7.
Subcellular Location:
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.
Tissue Specificity:
Ubiquitous. Expression was highest in heart and low in lung.
Similarity:
Belongs to the VPS18 family.
Contains 1 clathrin repeat.
Contains 1 RING-type zinc finger.
Gene ID:
57617
Database links:
Entrez Gene: 57617 Human
Entrez Gene: 228545 Mouse
Entrez Gene: 296083 Rat
Omim: 608551 Human
SwissProt: Q9P253 Human
SwissProt: Q8R307 Mouse
Unigene: 23876 Human
Unigene: 294761 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
空泡分选蛋白18抗体
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