英文名称 VILIP1
中文名称 神经视锥蛋白样1抗体(神经钙蛋白)
别 名 21 kDa CABP; Hippocalcin like protein 3; HLP 3; HLP3; HPCAL 3; HPCAL3; HUVISL1; Neural visinin-like protein 1; Neural visinin-like type 1 protein; Neurocalcin alpha; NVL 1; NVL1; Nvp1; OZ1; Ratnvp1; VILIP; Visinin; Visinin like 1; Visinin like protein 1; VISL 1; VISL1; Vnsl1; VISL1_HUMAN.
神经视锥蛋白样1抗体(神经钙蛋白)
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 神经生物学 信号转导
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human VILIP1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
神经视锥蛋白样1抗体(神经钙蛋白)产品介绍 background:
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Function:
Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner
Tissue Specificity:
Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level).
Similarity:
Belongs to the recoverin family.
Contains 4 EF-hand domains.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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