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缬氨酰-tRNA合成酶抗体

缬氨酰-tRNA合成酶抗体

价格: 面议

品牌:R&D

供货周期: 现货

货号:hz-10504R

型号:g/mg

英文名称    valyl tRNA    

中文名称    缬氨酰-tRNA合成酶抗体    

别    名    SYVM_HUMAN; Valine--tRNA ligase, mitochondrial; Valyl-tRNA synthetase; ValRS; Valyl-tRNA synthetase-like; valyl tRNA; VARS2; KIAA1885; VARS2L; VARSL.    

缬氨酰-tRNA合成酶抗体          

说 明 书    0.2ml      

研究领域    

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse, Sheep,     

产品应用    ICC=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    115kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human vars2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

缬氨酰-tRNA合成酶抗体    产品介绍    background:
ValRS (valyl-tRNA synthetase), also known as Protein G7a, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ValRS joins Val to tRNA(Val) at its synthetic active site. At its CP1 editing active site, ValRS hydrolyzes or deacylates tRNA(Thr) that is incorrectly joined to Val. ValRS forms aggregates with EF-1 (elongation factor 1) and, via this complex, catalyzes the aminoacylation of tRNA and its transfer to EF-1. In addition, ValRS may be regulated by PKC-dependent phosphorylation.

Function:


Subunit:


Subcellular Location:
Mitochondrion (Potential).

Tissue Specificity:


Post-translational modifications:


Similarity:
Belongs to the class-I aminoacyl-tRNA synthetase family.

Gene ID:
7407

Database links:

Entrez Gene: 7407 Human

Entrez Gene: 25009 Rat

Omim: 192150 Human

SwissProt: P26640 Human

SwissProt: Q04462 Rat

Unigene: 520026 Human

Unigene: 12314 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.     

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