获取电话英文名称 ZC3H12C
中文名称 ZC3H12C蛋白抗体
别 名 MCP induced protein 3; MCP-induced protein 3; MCPIP3; Probable ribonuclease ZC3H12C; ZC12C_HUMAN; ZC3H12C; Zinc finger CCCH domain-containing protein 12C.
ZC3H12C蛋白抗体
说 明 书 0.2ml
研究领域 细胞生物 免疫学 转录调节因子 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 99kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZC3H12C
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
ZC3H12C蛋白抗体 产品介绍 background:
ZC3H12C is an 883 amino acid protein that contains one C3H1-type zinc finger domain and belongs to the ZC3H12 family. ZC3H12C is suggested to function as an RNase, and thereby modifies levels of target RNA. Binding magnesium as a cofactor, ZC3H12C has been found to be induced in THP-1 cells when exposed toTNF?or IL-1. ZC3H12C is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia.
Function:
May function as RNase and regulate the levels of target RNA species.
Similarity:
Belongs to the ZC3H12 family.
Contains 1 C3H1-type zinc finger.
Database links:
Entrez Gene: 85463 Human
Entrez Gene: 244871 Mouse
Entrez Gene: 315658 Rat
Omim: 615001 Human
SwissProt: Q9C0D7 Human
SwissProt: Q5DTV4 Mouse
Unigene: 376289 Human
Unigene: 295686 Mouse
Unigene: 390172 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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