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仪器信息网试剂标物化学试剂有机试剂金雀异黄酮

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金雀异黄酮

价格：面议

品牌：AMRESCO

供货周期：现货

货号：XY-106673

规格：g/mg

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?金雀异黄酮

97%

Product Name: Genistein

别名:	金雀异黄酮 ;4',5,7-三羟基异黄酮,染料木黄酮, 染料木素
CAS号:	446-72-0
分子式:	C₁₅H₁₀O₅
分子量:	270.24
EINECS编号:	207-174-9
MDL号:	MFCD00016952

?金雀异黄酮

介绍:	溶于乙醇和DMSO，干冷处保存。
用途:	1、具有雌性激素及抗雌激素性质 2、在体内能抑制结肠癌、乳腺癌、皮肤癌、前列腺癌等 3、对多种肿瘤细胞株有抑制作用 4、具有抗氧化作用 5、可以抑制酪氨酸蛋白激酶（PTK）的活性 6、可以抑制拓扑异购酶Ⅱ的活性 7、可以预防绝经后骨质疏松 8、具有诱发细胞程序性死亡、提高抗癌药效、抑制血管生成等作用，是一种很有潜力的癌症化学预防剂，其抗癌作用及机制具有广泛的应用前景。
熔点:	297-298℃
特定比重:	1.548
贮存:	储存温度 -20°C
生化和生理学机理:	Description: IC50 Value: 37.5 uM( Topo II) [3] Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. It has been shown that genistein inhibits many type of cancers including prostate cancer (PCa) by regulating several cell signaling pathways and microRNAs (miRNAs). in vitro: GEN effectively reversed estrogenicity of BPA by reversing mRNA and protein expressions of ERα, IGF-1R, pIRS-1, and pAkt induced by BPA in cellular model and also significantly decreased tumor growth and in vivo expressions of ERα, pIRS-1, and pAkt in xenografted mouse model [1]. Interestingly, genistein and its analogs induced caspase 3-activation supporting apoptotic mechanism of cell death but SPG-G supported caspase 3-independent apoptosis [2]. Of the compounds tested, only genistein selectively inhibited human topo II activity and had an IC50 value of 37.5 ?M [3] in vivo: Genistein significantly decreased the blood levels of total cholesterol, triglycerides, homocysteine and visfatin compared with placebo, while blood adiponectin levels were increased [4]. Leucine and genistein significantly (p<0.05) reduced the number of fights and increased latency to fights in foot shock-induced aggression; it also decreased apomorphine (5mg/kg, i.p.) induced stereotyped behavior and apomorphine induced (10mg/kg, s.c.) locomotor activity when compared with the positive control group [5]. Clinical trial: Cholecalciferol and Genistein Before Surgery in Treating Patients With Early Stage Prostate Cancer. Phase 2

?金雀异黄酮

S0027 刚果红/直接刚果红/煮大红/棉红/直接朱红/直接大红/二苯基-4,4′-二［(偶氮2)-1-氨基萘-4-磺酸钠］/直接红28/3,3'-[[1,1'-联苯]-4,4'-基双(偶氮)]双(4-氨基萘-1-磺酸)二钠/风果红/直接大红4B /Congo red IND

AR，75%

S0027-1 刚果红试纸/Congo red test paper 100s/盒

S0028 虎红/玫瑰红/四氯四碘荧光素/孟加拉红/孟加拉玫瑰红B/酸性红94/Rose Bengal BR，90%

S0029 虎红钠盐/四氯四碘荧光素二钠/孟加拉玫瑰红B钠盐/Rose Bengal Na salt BR，90%

S0030 天狼星红BB/天狼星玫红BB/ 5,5’-[羟基双[亚氨(2-磺基-4,1-亚苯基)偶氮]]双(6-氨基-4-羟基)-2-萘磺酸四钠/直接红2B/直接红75/氯唑耐晒桃红/天狼猩红BB/Sirius Rose BB AR，30%

S0030-1 曙红B/伊红B/蓝光曙红/二溴二硝基荧光素二钠/4',5'-二溴-3',6'-二羟基-2',7'-二硝基螺(异苯并呋喃-1(3H),9'-(9H)占吨)-3-酮二钠盐/酸性红91/Eosin B BS，85%

S0031 曙红Y(水溶)/伊红Y(水溶) /水溶伊红/朝红/四溴荧光素二钠/曙红钠盐/四溴荧光黄/曙红变性次甲蓝/黄光曙红/曙红微黄/酸性红87/2',4',5',7'-四溴-3',6'-二羟基螺[异苯丙呋喃-1(3H),9'(9H)-占吨]-3-酮二钠盐/Eosin Y sodium salt water soluble BS，85%

高纯，88%

S0032 曙红Y(醇溶)/伊红Y(醇溶) /四溴荧光素/醇溶伊红/酸性红87/溶剂红43/曙红Y(自由酸)/伊红Y(自由酸)/ 2',4',5',7'-四溴-3',6'-二羟基螺[异苯丙呋喃-1(3H),9'(9H)-占吨]-3-酮/Eosin Y free acid alcohol soluble BS

S0034 油红O/1-［2,5-二甲基-4-(2,5-二甲基苯偶氮)苯偶氮］-2萘酚/苏丹红5B/溶剂红27/红油O/1-[[4-[(二甲基苯基)偶氮]二甲基苯基]偶氮]-2-萘酚/Oil red O 高纯，75%

S0035 丽春红S/猩红S/酸性红112/3-羟基-4-[2-磺酸基-4-(4-磺酸苯基偶氮)苯基偶氮]-2,7-萘二磺酸四钠盐/Ponceau S 高纯

S0035-1 丽春红2R/罂粟红R/罂粟红2R/丽春红G/酸性猩红/酸性大红/二甲苯胺丽春红/丽春红C/4-[(2,4-二甲苯基)偶氮]-3-羟基-2,7-萘二磺酸二钠盐/酸性红26/苯偶氮-8-乙酰苯胺基-1-萘酚-3,6-二磺酸钠盐/酸性偶氮红/Ponceau 2R 高纯

S0036 异硫氰酸玫瑰红B/异硫氰酸罗丹明B/罗丹明B异硫氰酸酯/若丹明B异硫氰酸酯/异硫氰酸若丹明B/RBITC 偶联级，70%

S0037 亚甲基蓝/次甲基兰/美蓝/美兰/亚甲蓝/品蓝/亚甲基兰/碱性蓝9/四甲基蓝/次甲基蓝/亚甲兰/碱性湖蓝BB/碱性亚甲天蓝/盐基湖蓝/盐基湖蓝BB/亚甲基天蓝/3,7-双(二甲氨基)吩噻嗪-5-翁氯化物/次甲基蓝三水/次甲蓝/甲稀蓝/氯化-3,7-双(二甲胺基)吩噻咛-5-鎓/Methylene Blue trihydratee BS

IND，82%

试剂级，98%

超纯

S0038 四溴酚兰/四溴酚蓝/四溴苯酚兰/TBPB IND，85%

S0039 伊文斯蓝/伊文斯兰/伊文思兰/偶氮蓝/依文氏兰/依文思蓝/依文斯兰/埃文斯蓝/6,6'-[[3,3'-二甲基(1,1'-二苯基)-4,4'-二基]双(偶氮基)]双(4-氨基-5-羟基-1,3-萘二磺酸)四钠盐/4,4’双[7-(1-氨基-8-羟基-2,4-二磺基)萘-偶氮]-3,3’-联甲苯上钠盐/伊文思蓝/埃文蓝/偶氮兰/Evans blue AR，80%

S0040 碘硝基氯化四氮唑蓝/碘硝基四唑紫/2-(对碘苯基)-3-(对硝基苯基)-5-苯基四唑氯水合物/2-(4-碘苯基)-3-(4-硝基苯基)-5-苯基氯化四唑氯水合物/碘硝基四氮唑紫/碘硝基四唑/碘硝基紫四唑/碘硝基氯化四氮唑/氯化-2-(4-磺苯)-3-(4-硝基苯)-5-苯基-2H-四氮唑/2-(对碘代苯)-3-(对硝基苯)-5-苯基氯化四氮唑/INT AR，98%

S0041 氯化硝基四氮唑蓝/氮蓝四唑/硝基蓝四氮唑/硝基BT/氯化硝基四氮唑兰/硝基氯化四氮唑蓝/氮四唑蓝/氯化四唑氮蓝/NBT BR，98%

S0042 靛蓝/还原靛蓝/印地科/靛青粉/靛兰(1)/还原蓝1#/靛/纯靛/铣傻謇叮合成靛青/2,2′-双氮茚型靛/Indigo CP，85%

S0042-1 靛蓝胭脂红/5,5′-靛蓝二磺酸二钠盐/靛红/酸性靛蓝/可溶靛/靛卡红/靛兰二磺酸钠/酸性蓝74/食品蓝1/靛胭脂/靛蓝洋红/靛蓝胭脂红二钠盐/腚兰胭脂红/食用靛蓝/靛深红/靛蓝-5,5'-二磺酸钠盐/2(1,3-二氢-3-氧代-5-磺基-2H-吲哚-2-亚基)-2,3-二氢-3-氧代-1H-吲哚-5-磺酸二钠盐/靛蓝二磺酸钠/食用色素蓝2号/Indigo carmine BS，85%

高纯，96%

S0043 百里酚蓝/百里香酚蓝/麝香草酚蓝/百里酚兰/百里香酚磺酞/百里香酚兰/4,4’-(3H-2,1-苯并恶硫羟-3-亚基)双[5-甲基-2-(1-甲基乙基)苯酚]-S,S-二氧化物/瑞香酚兰/Thymol blue IND

S0043-1 百里酚蓝钠/百里香酚蓝钠/麝香草酚蓝钠/百里酚兰钠/百里香酚磺酞钠/百里香酚兰钠/麝香草酚兰钠盐/瑞香草酚蓝/瑞香草酚磺酞/Thymol Blue sodium salt IND，98%

IND，0.04%

S0045 溴酚蓝/溴酚兰/四溴酚磺酞/四溴酚磺酚酞/四溴苯酚磺酞/四溴苯酚磺酰酞/3,3',5,5'-四溴磺酚酞/BPB IND

ACS

S0045-1 溴酚蓝钠/溴酚兰钠/溴甲酚蓝钠盐/Bromophenol blue sodium salt ACS

S0046 苯胺蓝（水溶）/苯胺兰水溶/酸性蓝22/水溶蓝/可溶性蓝/中国蓝/青瓷色/醇溶蓝/Aniline blue water soluble BS

S0047 甲苯胺蓝O/甲苯胺兰O/3-氨基-7-(二甲基氨基)-2-甲基吩噻嗪-5-翁氯化物/碱性蓝17/氯托洛宁/托洛氯铵/Toluidine blue O FMP，84%

S0047-1 甲苯胺蓝/甲苯胺兰/Toluidine bule BS，84%

S0048 溴百里香酚蓝/溴麝香草酚蓝/溴百里酚蓝/溴百里香酚兰/3,3′-二溴麝香草酚磺酰酞/3',3''-二溴百里香酚蓝/3,3ˊ-二溴麝香草酚磺酞/BTB IND

ACS

S0048-1 溴百里酚蓝钠盐/溴百里香酚蓝钠/溴百里香酚兰钠/溴麝香草酚蓝钠盐/3,3′-二溴麝香草酚磺酰酞钠/3',3''-二溴百里香酚蓝钠/3,3′-二溴百里酚磺酰酞钠/3,3'-二溴瑞香草酚磺酞钠/溴瑞香草酚蓝钠盐/Bromothymol blue sodium salt ACS

S0049 考马斯亮蓝G250/考马斯亮兰G250/酸性蓝90/考马斯亮蓝G/康美赛蓝G250/酸性艳蓝G/亮蓝/Coomassie brilliant blue G250 高纯

S0050 考马斯亮蓝R250/考马斯亮兰R250/酸性蓝83/酸性艳蓝6B/考马斯亮蓝R/考马斯灿烂蓝/康美赛蓝R250/Coomassie brilliant blue R250 高纯，65%

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