臂板蛋白3A抗体

英文名称    Sema3A    

中文名称    臂板蛋白3A抗体    

别    名    Semaphorin 3A; Semaphorin-3A; Semaphorin-3A precursor; Semaphorin3A; SemD; Sema 3A; SEM3A_MOUSE; Coll 1; Coll1; Hsema I; Hsema III; sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3A; Sema III; SEMA1; SEMA1-PEN; SEMA3A; SEMAD; SEMAIII; SEMAL; Semaphorin III; Semaphorin like growth cone guidance homolog of chick collapsin; Semaphorin III; Semaphorin-D; Sema D.    

 臂板蛋白3A抗体 

说 明 书    0.1ml  0.2ml  1ml    

研究领域    神经生物学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    86kDa    

细胞定位    分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from mouse Sema3A    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

 臂板蛋白3A抗体 产品介绍    background:
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Function:
Plays a role in growth cones guidance. May function to pattern sensory projections by selectively repelling axons that normally terminate dorsally. Involved in the development of the olfactory system and in neuronal control of puberty.

Subunit:
Interacts with PXND1.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed at relatively high levels in brain and muscle, moderate levels in lung, bursa, and heart and virtually absent in liver. Collapsin-1, -2, -3, and -5 bind to overlapping but distinct axon tracts.

Similarity:
Belongs to the semaphorin family. 
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. 
Contains 1 PSI domain. 
Contains 1 Sema domain.

Gene ID:
20346

Database links:

Entrez Gene: 10371 Human

Entrez Gene: 20346 Mouse

Entrez Gene: 29751 Rat

Omim: 603961 Human

SwissProt: Q14563 Human

SwissProt: O08665 Mouse

SwissProt: Q5BL08 Mouse

SwissProt: Q63548 Rat

Unigene: 252451 Human

Unigene: 44410 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.     

 臂板蛋白3A抗体 

hz-1331P sFRP-4(Secreted frizzled-related protein 4; Frizzled protein, human endometrium)  抗子宫内膜抗原

hz-0547P Endostatin  内皮抑素/内皮他丁抗原

hz-1249P EpCAM(Epithelial cell adhesion molecule)  上皮细胞粘附分子/表皮细胞粘附分子（多肽）

hz-1513P EpCAM/CD326(Epithelial cell adhesion molecule)  上皮细胞粘附分子/表皮细胞粘附分子抗原

hz-0658P E.coli O6 (Escherichia coli O6)  E.coli O6大肠杆菌菌体蛋白

hz-2100P EPEC/E.coli(enteropathogenic E．coli，EPEC)  普通大肠埃希菌菌体蛋白（非致病性）

hz-1763P EphA1 R(Ephrin A1 Receptor)  EphA1-R受体抗原

hz-1424P EPOR peptide  红细胞生成素受体抗原

hz-1522P phospho-ERK1/MAPK-1/2(pThr183 + pTyr185)  磷酸化丝裂原活化蛋白激酶1/2抗原

hz-0996P ERK(Extracellular signal-regulated kinase)  丝裂原活化蛋白激酶抗原

hz-1020P MAPK1/ERK3 (Mitogen-activated protein kinase 3; P44MAPK)  丝裂原活化蛋白激酶3抗原

hz-1319P MAPK4(Mitogen-activated protein kinase 4)  丝裂原活化蛋白激酶4抗原

hz-0894P ER- Alpha(phospho-Ser167)peptide  人磷酸化雌激素受体α多肽抗原

hz-1643P ER- Alpha(phospho-Tyr537)peptide  磷酸化雌激素受体α抗原

hz-0253P ER- Alpha /ER alpha peptide  雌激素受体α抗原

hz-2098P ER- Alpha/ER alpha peptide  雌激素受体α抗原

hz-0255P ER- Beta (Estrogen receptor-beta) peptide  雌激素受体β抗原

hz-1285P ets1/E26 (E-twenty six 1)  Ets转录因子家族ets1抗原

hz-0852P EV71(Human enterovirus 71)VP1  肠道病毒71型/手足口病病毒抗原

hz-0983P EV71(Human enterovirus 71)VP1(CT)  肠道病毒71型/手足口病病毒抗原(C端)

hz-2221P ATEXPA10 peptide  植物扩张蛋白ATEXPA10（拟南芥）抗原

hz-1343P Ezrin/Radixin  埃兹蛋白（多肽）

hz-0949P F1 operon positive regulatory protein(NT)  鼠疫耶尔森氏菌F1荚膜蛋白(N端多肽）

hz-0950P F1 operon positive regulatory protein(CT)  鼠疫耶尔森氏菌F1荚膜蛋白(C端多肽）

hz-2135P FABP(brain) (Fatty acid-binding protein brain)  脑型脂肪酸结合蛋白抗原

hz-0511P FADD (Fas-associated protein with death domain)  Fas死亡结构域相关蛋白抗原

hz-1340P FAK(Focaladhesin kinase)  粘着斑激酶抗原

hz-1639P phospho-FAK(pTyr577)  磷酸化粘着斑激酶抗原

hz-1642P phospho-FAK(pSer732)(phospho-Focal adhesion kinase)  磷酸化粘着斑激酶抗原

hz-1765P FAST kinase(Fas-activated serine/threonine kinase)  Fas活化的丝/苏氨酸激酶抗原

hz-1157P FBN1 (fibrillin 1)  原纤维蛋白1抗原

hz-1256P FGF4/HSTF1/HBGF-4(Fibroblast Growth Factor4)  纤维母细胞生长因子4抗原

hz-1257P FGF5 peptide  纤维母细胞生长因子5抗原

hz-0809P Fibulin 1  衰老关键蛋白抗原

hz-1462P FLG(filaggrin)peptide  丝聚蛋白/中间丝蛋白抗原