丝氨酸合并蛋白3抗体（肿瘤差异表达蛋白）

英文名称    SERINC3    

中文名称    丝氨酸合并蛋白3抗体（肿瘤差异表达蛋白）    

别    名    TMS 1; TMS-1; AIGP1; DIFF33; SBBI99; serine incorporator 3; TDE; TDE1; Tumor differentially expressed protein 1; SERC3_HUMAN.    

丝氨酸合并蛋白3抗体（肿瘤差异表达蛋白）     

说 明 书    0.2ml      

研究领域    肿瘤  免疫学  肿瘤细胞生物标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    53kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SERINC3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

丝氨酸合并蛋白3抗体（肿瘤差异表达蛋白）产品介绍    background:
TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.

Function:
May be involved in cellular transformation.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the TDE1 family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

丝氨酸合并蛋白3抗体（肿瘤差异表达蛋白）

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hz-5400R Phospho-c-Kit(Ser741)  磷酸化原癌基因c-kit抗体

hz-0395R CD133 antigen  造血干细胞抗原CD133抗体

hz-5814R Prominin 2  造血干细胞抗原CD133相关蛋白抗体

hz-0209R CD133 antigen  造血干细胞抗原CD133抗体

hz-2449R CD137/TNFRSF9  肿瘤坏死因子受体超家族成员9抗体

hz-1309R CD138/Syndecan 1  多配体蛋白聚糖1抗体

hz-1618R CD146/MCAM  黑色素瘤细胞粘附分子CD146抗体

hz-5472R phospho-MCAM(Tyr641)  磷酸化黑色素瘤细胞粘附分子CD146抗体

hz-1783R CD141/THBD  凝血调节蛋白/血栓调节素抗体

hz-4132R Ron  原癌基因c-Met相关酪氨酸激酶抗体

hz-5489R phospho-MST1R(Ser1349)  磷酸化原癌基因c-Met相关酪氨酸激酶抗体

hz-5490R phospho-MST1R(Tyr1238)  磷酸化原癌基因c-Met相关酪氨酸激酶抗体

hz-4138R MAPK11/p38Beta  丝裂原活化的蛋白激酶p38β抗体

hz-5506R phospho-MAPK11(Thr180+Tyr182)  磷酸化丝裂原活化的蛋白激酶p38β抗体

hz-4141R NUDEL/NDEL1  中心粒蛋白Nudel抗体

hz-4212R Neuroligin 1  突触细胞粘附分子1抗体

hz-5522R phospho-NDEL1(Ser231)  磷酸化中心粒蛋白Nudel抗体

hz-5523R phospho-NDEL1(Ser242)  磷酸化中心粒蛋白Nudel抗体

hz-5524R phospho-NDEL1(Thr219)  磷酸化中心粒蛋白Nudel抗体

hz-1383R CD13/APN/ANPEN  CD13氨肽酶N抗体

hz-1192R CD14  内毒素受体抗体

hz-2491R CD27/TNFRSF7  CD27抗体

hz-1297R CD28  CD28抗体

hz-0878R CD144/VECD/VE Cadherin  上皮型钙粘附分子抗体

hz-4142R NPTX1  神经细胞正五聚体1抗体

hz-5527R phospho-NPTX1(Tyr344)  磷酸化神经细胞正五聚体1抗体

hz-0684R CD147/TCSF/hzmprin  细胞外基质金属蛋白酶诱导因子抗体

hz-2526R CD160/By55  NK细胞受体BY55抗体

hz-2807R CD161   CD161抗体

hz-4682R CD161c/NK1.1  CD161抗体

hz-2527R CD163/M130  CD163抗体