获取电话英文名称 FUBP3
中文名称 远端上游元件结合蛋白3抗体
别 名 Far upstream element (FUSE) binding protein 3; Far upstream element binding protein 3; Far upstream element-binding protein 3; FBP3; FLJ25229; FUBP 3; FUBP3; FUBP3_HUMAN; FUSE binding protein 3; FUSE-binding protein 3; OTTHUMP00000022369.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 信号转导 转录调节因子 细胞分化 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 远端上游元件结合蛋白3抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
细胞定位 细胞核
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FUBP3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
远端上游元件结合蛋白3抗体产品介绍 background:
Activation of FUSE, the far-upstream element, is required for the proper ex-pression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein or Far upstream element binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxyl-terminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation.
Function:
May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.
Subcellular Location:
Nucleus.
Tissue Specificity:
Detected in a number of cell lines.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Contains 4 KH domains.
Database links:
UniProtKB/Swiss-Prot: Q96I24.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
远端上游元件结合蛋白3抗体
hz-0082P CASP4(Caspase-4) 半胱胺酸蛋白酶蛋白-4抗原
hz-0175P Trk B 神经生长因子受体的一种（抗原）
hz-2227P GDF8/MSTN(growth differntiation factor 8) 重组生长分化因子8/肌肉抑制素
hz-0288P Trk B 神经生长因子受体的一种（抗原）
hz-0855P Insulin protein (Active) 重组人胰岛素细胞因子
hz-0176P Trk C 神经生长因子受体的一种（抗原）
hz-0003P TSHR (Thyroid stimulating hormone receptor)(NT) 促甲状腺素受体（抗原）
hz-0052P Caspase-8 (pro Mch5) 半胱氨酸蛋白酶8抗原
hz-0206P TSHR (Thyroid stimulating hormone receptor)(CT) 促甲状腺素受体（抗原）
hz-0016P TY3H ( Tyrosine Hydroxylase ) 酪氨酸羟化酶（抗原）
hz-0159P Tubulin-Alpha 微管蛋白（抗原）
hz-1453P Cav-1/ETM1 peptide 细胞质膜微囊蛋白-1抗原
hz-1165P Beta-catenin/ Beta-cats β-连环蛋白抗原（β-β链接素）
hz-2063P p- Beta catenin(p-beta Catenin(phosphor-Y142)) 磷酸化β-连环蛋白抗原
hz-0210P Tubulin- Beta 微管蛋白（抗原）
hz-0452P NAIF1 protein( CB12-327) 核凋亡诱导因子蛋白1(多肽)
hz-1500P cath-B/CB(Cathepsin B) 组织蛋白酶B抗原
hz-1508P cath-L/CL peptide 组织蛋白酶L抗原
hz-1134P CBFA1/RUNX2 (Runt-related Transcription Factor 2) 成骨特异性转录因子（多肽）
hz-1397P CBP(CREB-binding protein) CREB结合蛋白抗原
hz-1421P CBX3/HP1 gamma 染色盒同源物3抗原
hz-0955P CBX5(Chromobox Homolog 5) CBX5（多肽）
hz-1487P CC16(Clara cell protein 16) peptide 克拉拉细胞蛋白(Clara细胞分泌蛋白)抗原
hz-0562P CCR-2/5(CC chhzokine receptor 2/5) CC趋化因子受体2/5抗原
hz-2450P CCL1/TCA3/I-309 嗜酸粒细胞趋化蛋白CCL1抗原
hz-1324P CCL5/RANTES(regulated on activation normal T cell expressed and secreted) 活化T细胞表达和分泌的调节因子抗原
hz-2475P CCL4/MIP-1 Beta(Macrophage Inflammatory Protein 1 beta) 巨噬细胞炎性蛋白1β抗原
hz-1268P MIP3 Alpha/CCL20(Macrophage inflammatory ptotein 3 alpha) 巨噬细胞炎性蛋白3α抗原
hz-2478P CCL12/MCP-5(C-C motif chhzokine 12) 单核细胞趋化蛋白5抗原
hz-2479P CCL14/HCC-1(C-C motif chhzokine 14) 嗜酸粒细胞趋化蛋白14抗原
hz-1761P ABCD-1/CCL22 嗜酸粒细胞趋化蛋白22抗原
hz-2454P MIP-3 beta/ELC/CCL19(Macrophage Inflammatory Protein 3 Beta) 巨噬细胞炎性蛋白19抗原
