锌指蛋白798抗体

英文名称    FIZ1    

中文名称    锌指蛋白798抗体    

别    名    FLJ00416; FLJ14768; FLT3 interacting zinc finger 1; Flt3 interacting zinc finger protein 1; Zinc finger protein 798; ZNF798; FIZ1_HUMAN.    

说 明 书    0.2ml      

研究领域    细胞生物  神经生物学  转录调节因子  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 锌指蛋白798抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    52kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human FIZ1/ZNF798    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

锌指蛋白798抗体产品介绍    background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. FIZ1 (FLT3-interacting zinc finger 1), also known as ZNF798 (zinc finger protein 798), is a 496 amino acid zinc-finger protein that contains eleven C2H2-type zinc fingers. Localized to both the cytoplasm and the nucleus and expressed in a wide variety of tissues, FIZ1 is thought to repress the function of Nrl (neural retina leucine zipper) in photoreceptors, possibly regulating the expression of rod-specific genes. Additionally, FIZ1 interacts with the receptor-related tyrosine kinase Flt-3/Flk-2 and, via this interaction, may be involved in the regulation of lymphoid and hematopoietc cells.

Function:
FIZ1 is a zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. It also interacts with a transcription factor that regulates the expression of rod-specific genes in retina.

Subunit:
Interacts with FLT3 cytoplasmic catalytic domain, following receptor stimulation, in a kinase-independent manner. Does not interact with other structurally related receptor tyrosine kinases, including KIT, CSF1R and PDGFR. Interacts with NRL (By similarity). 

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Widely expressed. 

Similarity:
Contains 11 C2H2-type zinc fingers.

Database links:

Entrez Gene: 84922 Human

Omim: 609133 Human

SwissProt: Q96SL8 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

锌指蛋白798抗体

hz-1933R WNT9A  信号通路Wnt9a抗体

hz-1946R WNT2B  信号通路Wnt2B抗体

hz-1948R WNT5A  信号通路Wnt5a抗体

hz-1947R WNT10A  信号通路WNT10A抗体

hz-3662R WNT12/WNT10B  信号通路WNT10B抗体

hz-1944R WRCH-1  WRCH1抗体

hz-0589R WWOX  包含氧化还原酶的WW域抗体

hz-3605R YAP1  原癌基因Yes相关蛋白1抗体

hz-3475R Phospho-YAP1(Ser127)  磷酸化原癌基因Yes相关蛋白1抗体

hz-3476R Phospho-YAP1(Tyr407)  磷酸化原癌基因Yes相关蛋白1抗体

hz-1943R YB1  y-盒结合蛋白1抗体

hz-3477R Phospho-YB1(Ser102)  磷酸化DNA结合蛋白B抗体

hzm-1265M F1 protein (YERSINIA PESTIS)  鼠疫F1蛋白/鼠疫耶尔森氏菌荚膜抗原F1单克隆抗体

hz-1281R XIAP/BIRC4  X-连锁凋亡蛋白/性连锁凋亡抑制蛋白抗体

hz-1415R YY1  核转录调节因子YY1抗体

hz-1308R XAF1/FBXO39  XIAP相关因子1凋亡抑制蛋白抗体

hz-1218R XRCC1  X射线修复交叉互补蛋白抗体

hz-4261R XRCC3  X射线修复交叉互补蛋白3抗体

hz-1668R XBP-1  细胞核转录因子X盒结合蛋白抗体

hz-1942R ZAP-70  zeta相关蛋白70抗体

hz-3478R Phospho-Zap-70 (Tyr315/Tyr319)  磷酸化zeta相关蛋白70抗体

hz-3479R Phospho-Zap-70(Tyr493)  磷酸化zeta相关蛋白70抗体

hz-4106R FANCG  DNA损伤修复基因XRCC9抗体

hz-5353R phospho-FANCG (Ser383)  磷酸化DNA损伤修复基因XRCC9抗体

hz-0354R ZCWCC1  ZCWCC1抗体

hz-1941R Zfp91  白血病相关新基因抗体

hz-2510R ZNF217  锌指脂蛋白217抗体

hz-0626R ZNF268  锌指脂蛋白-1b抗体

hz-0627R ZNF268  锌指脂蛋白-1c抗体

hz-0625R ZNF268  锌指脂蛋白抗体

hz-0628R ZNF300  锌指蛋白300抗体

hz-1940R ZNF307  锌指蛋白307抗体

hz-6120R ZNF431  锌指蛋白431抗体

hz-1939R ZNF474/ZFP106  锌指蛋白474抗体