法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体

英文名称    FDFT1    

中文名称    法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体    

别    名    DGPT; ERG9; Farnesyl diphosphate farnesyltransferase 1; Farnesyl diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; FDFT_HUMAN; FDFT1; FPP:FPP farnesyltransferase; Presqualene di diphosphate synthase; SQS; Squalene synthase; Squalene synthetase; SS.    

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  神经生物学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog,     

产品应用    IHC-P=1:100-500 IHC-F=1:100-500 法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    48kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human FDFT1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体产品介绍    background:

Several proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.

Function:
Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.

Subunit:
Monomer

Subcellular Location:
Endoplasmic reticulum membrane.

Similarity:
Belongs to the phytoene/squalene synthase family.

Gene ID:
2222

Database links:

Entrez Gene: 2222 Human

Entrez Gene: 14137 Mouse

Omim: 184420 Human

SwissProt: P37268 Human

SwissProt: P53798 Mouse

Unigene: 593928 Human

Unigene: 474432 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

法尼基二磷酸法尼基转移酶1/鲨烯合成酶抗体

hz-4552R H1N1 Matrix Protein 1  A型禽流感病毒H1N1蛋白抗体

hz-0422R H1N1 Matrix Protein 2/Influenza A bp1   A型猪流感病毒H1N1-M2蛋白抗体

hz-2001R H1N1 Hhzagglutinin 1/Influenza A bp1  甲型流感病毒血凝素抗体

hz-4544R H9N1 Neuraminidase  A型流感病毒H9N1神经氨酸酶型抗体

hz-2002R H1N1 Hhzagglutinin 1/HA probe  甲型流感病毒血凝素抗体

hz-1690R H2N2 Hhzagglutinin  甲型流感病毒血凝素抗体（H2N2）

hz-3779R Histone H2A  组蛋白H2A抗体

hz-3781R Acetyl-Histone H2A(K5)  乙酰化组蛋白H2A抗体

hz-2560R Histone H2A.x  组蛋白H2AX抗体

hz-3185R Phospho-Histone H2A.X (Ser139)  磷酸化组蛋白H2AX抗体

hz-5360R Phospho-Histone H2A.X (Tyr143)  磷酸化组蛋白H2AX抗体

hz-3652R Histone H2B  组蛋白H2B抗体

hz-3782R Acetyl-Histone H2B(K5)  乙酰化组蛋白H2B抗体

hz-3783R Acetyl-Histone H2B(K20)  乙酰化组蛋白H2B抗体

hz-2003R H1N1 Hhzagglutinin 2  甲型流感病毒血凝素抗体

hz-2004R H1N1 Hhzagglutinin 2  甲型流感病毒血凝素抗体

hz-4619R H1N1/H5N1/H3N2 nucleocapsid protein  A型流感病毒核衣壳蛋白抗体

hz-4620R H1N1/H5N1/H3N2 nucleocapsid protein  A型流感病毒核衣壳蛋白抗体

hz-4621R H1N1/H5N1/H3N2 nucleocapsid protein  A型流感病毒核衣壳蛋白抗体

hz-5888R Hyaluronidase2  透明质酸酶2/玻璃酸酶2抗体

hz-1235R Hyaluronidase-PH20/Haase  透明质酸酶/玻璃酸酶抗体

hz-3837R Hamartin/TSC1  结节性硬化症蛋白1抗体

hz-5600R phospho-TSC1(Ser505)  磷酸化结节性硬化症蛋白1抗体

hz-3653R SCHAD/HADHSC  短链L-3羟烷基辅酶A脱氢酶抗体

hz-3661R SCHAD/HADHSC(mouse, rat)  短链L-3羟烷基辅酶A脱氢酶抗体（小鼠，大鼠）

hz-5606R phospho-TSC1(Thr417)  磷酸化结节性硬化症蛋白1抗体

hz-5889R Hyaluronidase3  透明质酸酶2/玻璃酸酶2抗体

hz-2424R KCNH1/EAG1  钾离子通道蛋白EAG1抗体

hz-5123R Anterior Gradient 2  前梯度同源蛋白2抗体

hz-1815R HERG/KCNH2/ERG  特异性钾离子通道蛋白抗体

hz-2713R HAVCR1/TIM1  肾损伤分子1抗体（甲型肝炎病毒细胞受体1）

hz-0843R HA tag  HA tag标签抗体

hz-0966R HA tag  HA tag标签抗体