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FAM29蛋白抗体

FAM29蛋白抗体

价格: 面议

品牌:R&D

供货周期: 现货

货号:hz-9723R

型号:g/mg

英文名称    FAM29A    

中文名称    FAM29蛋白抗体    

别    名    Dgt6; Dim gamma tubulin homolog; Family with sequence similarity 29 member A; FLJ20060; HAUS augmin like complex subunit 6; HAUS6; KIAA15741; HAUS6_HUMAN.    

说 明 书    0.2ml      

研究领域    细胞生物  免疫学  神经生物学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 FAM29蛋白抗体(石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    109kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human FAM29A/HAUS6    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

FAM29蛋白抗体产品介绍    background:

The human augmin complex (HAUS) is an evolutionarily conserved 8-subunit protein complex that was initially discovered in Drosophila. The HAUS complex is essential for microtubule generation, centrosome integrity, mitotic spindle assembly and completion of cytokinesis. HAUS6 (HAUS augmin-like complex, subunit 6), also known as FAM29A or Dgt6, is a 955 amino acid component of the augmin complex. Required for mitotic progression, HAUS6 localizes to cytoplasm, cytoskeleton, mitotic spindle microtubules and interphase centrosomes, and undergoes post-translational phosphorylation following mitosis on multiple serine and threonine residues. HAUS6 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 9.

Function:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin. 

Subunit:
Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. Interacts with PLK1 and NEDD1.

Subcellular Location:
Cytoplasm, Cytoskeleton, Microtubule

Post-translational modifications:
Phosphorylated during mitosis. 

Similarity:
Belongs to the HAUS6 family. 

Database links:

Entrez Gene: 54801 Human

Omim: 613433 Human

SwissProt: Q7Z4H7 Human

Unigene: 533468 Human


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

FAM29蛋白抗体

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hz-4616R CD54/ICAM-1  细胞间粘附分子-1抗体




生化试剂 FAM29蛋白抗体 由上海沪震生物科技有限公司为您提供,如想了解更多关于抗体/抗原 FAM29蛋白抗体 的报价、规格、厂家等信息,欢迎来电或留言咨询。除供应FAM29蛋白抗体 外,上海沪震生物科技有限公司还可为您提供: 猴子巨噬细胞移动抑制因子(MIF)ELISA试剂盒、 豚鼠γ干扰素(IFN-γ)ELISA试剂盒 、 山羊丙酮检测(acetone)ELISA试剂盒

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