获取电话英文名称 FNDC5
中文名称 Ⅲ型纤维连接蛋白域蛋白2/5抗体
别 名 FNDC5; Fibronectin type III domain containing 5; Fibronectin type III domain-containing protein 5; Fibronectin type III repeat containing protein 2; Fibronectin type III repeat-containing protein 2; FNDC 5; Fndc5; FNDC5_HUMAN; FRCP2; Irisin.
说 明 书 0.2ml
研究领域 细胞生物 免疫学 G蛋白信号
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200 Ⅲ型纤维连接蛋白域蛋白2/5抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12/20kDa
细胞定位 细胞浆 细胞膜 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FNDC5 Irisin
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Ⅲ型纤维连接蛋白域蛋白2/5抗体产品介绍 background:
This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013].
Function:
Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity).
Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein (By similarity). Note=Imported in peroxisomes through the PEX5 receptor pathway (By similarity).
Irisin: Secreted. Note=Detected in the blood of individuals subjected to endurance exercise.
Post-translational modifications:
The extracellular domain is cleaved and released from the cell membrane.
N-Glycosylated.
Similarity:
Contains 1 fibronectin type-III domain.
Database links:
UniProtKB/Swiss-Prot: Q8NAU1.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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Ⅲ型纤维连接蛋白域蛋白2/5抗体 多少钱?
R&D抗体/抗原的应用资料有吗？
R&D抗体/抗原货号hz-8486R报价含票含运吗？
R&D货号hz-8486R货期是多久？
沪震生物Ⅲ型纤维连接蛋白域蛋白2/5抗体 可以申请试用吗？
沪震生物R&D抗体/抗原售后政策是什么？
Ⅲ型纤维连接蛋白域蛋白2/5抗体 有现货吗？
