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肾母细胞瘤基因X染色体蛋白抗体

肾母细胞瘤基因X染色体蛋白抗体

价格: 面议

品牌:R&D

供货周期: 现货

货号:hz-6131R

型号:g/mg

英文名称    FAM123B    

中文名称    肾母细胞瘤基因X染色体蛋白抗体    

别    名    CCN family member 5; CCN5; Connective tissue growth factor like protein; Connective tissue growth factor related protein 58; Connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; CT58; CTGF L; CTGF-L; WISP 2; WISP-2; Wisp2; WISP2_HUMAN; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2.    

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  信号转导  干细胞  细胞周期蛋白  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 肾母细胞瘤基因X染色体蛋白抗体(石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    24kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human FAM123B/AMER1/Wilms tumor on the X    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

肾母细胞瘤基因X染色体蛋白抗体产品介绍    background:

his gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. 

Function:
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.

Subunit:
Secreted 

Tissue Specificity:
Expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. 

Similarity:
Belongs to the CCN family. 
Contains 1 IGFBP N-terminal domain. 
Contains 1 TSP type-1 domain. 
Contains 1 VWFC domain.     

肾母细胞瘤基因X染色体蛋白抗体

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hz-3874R ALOX12/12 Lipoxygenase  12脂氧合酶抗体

hz-2036R Penicillin G  青霉素G抗体

hz-1278R 8-OHdG  8-羟基脱氧鸟苷抗体

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hz-4235R ADORA1  腺苷A1A受体抗体

hz-2077R AMP deaminase 1  腺苷单磷酸脱氨酶1抗体

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生化试剂 肾母细胞瘤基因X染色体蛋白抗体 由上海沪震生物科技有限公司为您提供,如想了解更多关于抗体/抗原 肾母细胞瘤基因X染色体蛋白抗体 的报价、规格、厂家等信息,欢迎来电或留言咨询。除供应肾母细胞瘤基因X染色体蛋白抗体 外,上海沪震生物科技有限公司还可为您提供: 猴子巨噬细胞移动抑制因子(MIF)ELISA试剂盒、 豚鼠γ干扰素(IFN-γ)ELISA试剂盒 、 山羊丙酮检测(acetone)ELISA试剂盒

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