英文名称 Follistatin
中文名称 卵泡抑素抗体
别 名 Activin binding protein; FS; Follistatin; Activin-binding protein; FS; fst; FST_HUMAN; Human follistatin gene.
说 明 书 0.1ml 0.2ml
研究领域 免疫学 生长因子和激素
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 卵泡抑素抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
细胞定位 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Follistatin
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
卵泡抑素抗体产品介绍 background:
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. There is evidence linking polycystic ovary syndrome and follistatin.
Follistatin binds directly to activin and functions as an activin antagonist. It specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone.
Subunit:
Monomer (Potential).
Subcellular Location:
Secreted.
Tissue Specificity:
Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.
Similarity:
Contains 3 follistatin-like domains.
Contains 3 Kazal-like domains.
Contains 1 TB (TGF-beta binding) domain.
Gene ID:
10468
Database links:
Entrez Gene: 396119 Chicken
Entrez Gene: 327681 Cow
Entrez Gene: 10468 Human
Entrez Gene: 14313 Mouse
Entrez Gene: 445002 Pig
Entrez Gene: 24373 Rat
Omim: 136470 Human
SwissProt: Q90844 Chicken
SwissProt: P50291 Cow
SwissProt: P19883 Human
SwissProt: P47931 Mouse
SwissProt: P10669 Pig
SwissProt: P21674 Rat
Unigene: 9914 Human
Unigene: 4913 Mouse
Unigene: 162557 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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