获取电话英文名称 ATP6IP2
中文名称 ATP酶H+转运溶酶体辅助蛋白2抗体
别 名 APT6M8 9; ATP6AP2; ATP6M8-9; ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ATPase H+ transporting lysosomal accessory protein 2; ATPase H+ transporting lysosomal interacting protein 2; ATPase H+ transporting lysosomal vacuolar proton pump membrane sector associated protein M8 9; ATPase membrane sector associated protein M8 9; CAPER; ELDF10; Embryonic liver differentiation factor 10; ER localized type I transmembrane adaptor; ER-localized type I transmembrane adaptor; HT028; M8 9; MRXE; N14F; Renin receptor; Renin/prorenin receptor; RENR_HUMAN; V ATPase M8 9 subunit; V ATPase M8.9 subunit; V-ATPase M8.9 subunit; Vacuolar ATP synthase membrane sector associated protein M8 9; Vacuolar ATP synthase membrane sector-associated protein M8-9; vacuolar proton ATP synthase membrane sector associated protein M8 9; XMRE.
说 明 书 0.2ml
研究领域 细胞生物 通道蛋白 转运蛋白 细胞表面分子
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 ATP酶H+转运溶酶体辅助蛋白2抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ATP6IP2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ATP酶H+转运溶酶体辅助蛋白2抗体产品介绍 background:
This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq, Jul 2008].
Function:
Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).
Subunit:
Interacts with renin and the vacuolar proton-ATPase.
Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).
Tissue Specificity:
Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.
Post-translational modifications:
Phosphorylated.
DISEASE:
Defects in ATP6AP2 are a cause of mental retardation X-linked with epilepsy (MRXE) [MIM:300423]. MRXE is a syndromic mental retardation. Patients manifest mild to moderate mental retardation associated with epilepsy, delays in motor milestones and speech acquisition in infancy.
Database links:
UniProtKB/Swiss-Prot: O75787.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ATP酶H+转运溶酶体辅助蛋白2抗体
hz-2098P ER- Alpha/ER alpha peptide 雌激素受体α抗原
hz-0255P ER- Beta (Estrogen receptor-beta) peptide 雌激素受体β抗原
hz-1285P ets1/E26 (E-twenty six 1) Ets转录因子家族ets1抗原
hz-0852P EV71(Human enterovirus 71)VP1 肠道病毒71型/手足口病病毒抗原
hz-0983P EV71(Human enterovirus 71)VP1(CT) 肠道病毒71型/手足口病病毒抗原(C端)
hz-2221P ATEXPA10 peptide 植物扩张蛋白ATEXPA10（拟南芥）抗原
hz-1343P Ezrin/Radixin 埃兹蛋白（多肽）
hz-0949P F1 operon positive regulatory protein(NT) 鼠疫耶尔森氏菌F1荚膜蛋白(N端多肽）
hz-0950P F1 operon positive regulatory protein(CT) 鼠疫耶尔森氏菌F1荚膜蛋白(C端多肽）
hz-2135P FABP(brain) (Fatty acid-binding protein brain) 脑型脂肪酸结合蛋白抗原
hz-0511P FADD (Fas-associated protein with death domain) Fas死亡结构域相关蛋白抗原
hz-1340P FAK(Focaladhesin kinase) 粘着斑激酶抗原
hz-1639P phospho-FAK(pTyr577) 磷酸化粘着斑激酶抗原
hz-1642P phospho-FAK(pSer732)(phospho-Focal adhesion kinase) 磷酸化粘着斑激酶抗原
hz-1765P FAST kinase(Fas-activated serine/threonine kinase) Fas活化的丝/苏氨酸激酶抗原
hz-1157P FBN1 (fibrillin 1) 原纤维蛋白1抗原
hz-1256P FGF4/HSTF1/HBGF-4(Fibroblast Growth Factor4) 纤维母细胞生长因子4抗原
hz-1257P FGF5 peptide 纤维母细胞生长因子5抗原
hz-0809P Fibulin 1 衰老关键蛋白抗原
hz-1462P FLG(filaggrin)peptide 丝聚蛋白/中间丝蛋白抗原
hz-1170P FOS B FosB抗原
hz-1188P FRA2/FOSL2(Fos related/like antigen 2) FOS样抗原2
hz-2585P FOXF1(Forkhead box protein F1) 叉头蛋白F1抗原
hz-1775P FOXJ1/HFH-4 peptide 插头蛋白J1抗原
hz-1275P FoxP1(Forkhead box P1) FoxP1（T细胞转录因子）抗原
hz-2687P FOXM1/HFH 11 peptide 插头蛋白M1抗原
hz-0886P Measles virus of fusion protein 麻疹病毒抗原（麻疹病毒融合蛋白）
hz-0895P FSH-R(Follicle-stimulating hormone receptor precursor) 促卵泡刺激素受体抗原
hz-1536P FSH(Follicle-stimulating hormone precursor) 促卵泡刺激素抗原
hz-1232P GABRA1(gamma-aminobutyric acid (GABA) A receptor, alpha 1) γ1氨基丁酸A型受体α1抗原
hz-0533P GABAB1(GABAb Receptor 1) g-氨基丁酸B1受体(多肽)
hz-1293P GABABR2/GB2(GABA B Receptor 2) γ1氨基丁酸A型受体B2抗原
