细胞凋亡增强核酸酶抗体

英文名称    Apoptosis enhancing nuclease    

中文名称    细胞凋亡增强核酸酶抗体    

别    名    Aen; AEN_HUMAN; apoptosis enhancing nuclease; Apoptosis-enhancing nuclease; Interferon stimulated exonuclease gene 20kDa like 1; Interferon stimulated exonuclease gene 20kDa like 1, isoform CRA_a; Interferon-stimulated 20 kDa exonuclease-like 1; ISG20L1; pp12744.    

说 明 书    0.2ml      

研究领域    细胞生物  染色质和核信号  信号转导  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 细胞凋亡增强核酸酶抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    36kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Apoptosis enhancing nuclease (31-55aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

细胞凋亡增强核酸酶抗体产品介绍    background:

Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.

Function:
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.

Subcellular Location:
Nucleus. Nucleus, nucleolus. Note=Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction. 

Similarity:
Contains 1 exonuclease domain. 

Database links:
UniProtKB/Swiss-Prot: Q8WTP8.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

细胞凋亡增强核酸酶抗体

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hz-1155P ASCL1/MASH1(Achaete-scute homolog 1)  神经母细胞特异性转移因子抗原

hz-1282P ASPP1(apoptosis stimulating protein of P53 1)  p53凋亡刺激蛋白1抗原

hz-1283P ASPP2(apoptosis stimulating protein of P53 2)  P53凋亡刺激蛋白2抗原

hz-0289P neurofasciu-155  神经束蛋白-155

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hz-0630P AT1R(Angiotensin II Type 1 Receptor)  血管紧张素Ⅱ-1型受体抗原

hz-2097P AT1R/AGTR1(Angiotensin II Type 1 Receptor)  血管紧张素Ⅱ-1型受体抗原

hz-0074P NIK，NF-kappaB-Inducing Kinase  NFkB诱导的激酶（抗原）

hz-0517P ATF1 (Activating Transcription Factor1)  活化复制因子1

hz-0070P NKB (Neurokinins B)  神经激肽B（抗原）

hz-0518P ATF2 (Activating Transcription Factor2)  活化复制因子2（多肽）

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hz-0519P ATF3 (Activating Transcription Factor3)  活化转录因子3抗原

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hz-1634P ATF6(activating transcription factor 6)  活化转录因子6抗原

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hz-2436P Kir6.2 peptide  ATP敏感性钾通道亚基kir6.2抗原

hz-1705P AVPR2(arginine vasopressin receptor 2)  精氨酸加压素受体2抗原

hz-2445P Aurora B  极光激酶B抗原

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