ELOVL1蛋白抗体

英文名称    ELOVL1    

中文名称    ELOVL1蛋白抗体    

别    名    3 keto acyl CoA synthase ELOVL1; 3-keto acyl-CoA synthase ELOVL1; CGI 88; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1; Elongation of very long chain fatty acids like 1; Elongation of very long chain fatty acids protein 1; ELOV1_HUMAN; ELOVL 1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; ELOVL1; Ssc1; very long chain 3 oxoacyl CoA synthase 1; Very-long-chain 3-oxoacyl-CoA synthase 1.    

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  神经生物学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 ELOVL1蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    33kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ELOVL1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

ELOVL1蛋白抗体产品介绍    background:

Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism. 

Function:
Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Subunit:
Interacts with LASS2, TECR and HSD17B12.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the ELO family.

Gene ID:
64834

Database links:

Entrez Gene: 64834 Human

Entrez Gene: 54325 Mouse

Omim: 611813 Human

SwissProt: Q9BW60 Human

SwissProt: Q9JLJ5 Mouse

Unigene: 25597 Human

Unigene: 282096 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

ELOVL1蛋白抗体

hz-2898R IKK gamma/IKBKG  KB抑制蛋白激酶γ抗体

hz-1156R NFKBIB/IKB beta  核因子κB抑制蛋白β抗体

hz-3191R Phospho-NFKBIB (Ser23)   磷酸化KB抑制蛋白β抗体

hz-1287R NFKBIA/IKB alpha  核因子κB抑制蛋白α抗体

hz-3229R IKKα(Phospho-Thr23)  磷酸化KB抑制蛋白激酶α抗体

hz-3234R phospho-IKK alpha (Tyr463)  磷酸化KB抑制蛋白激酶α抗体

hz-3235R phospho-IKK alpha (Ser176 + Ser180)  磷酸化KB抑制蛋白激酶α抗体

hz-3236R Phospho-IKK alpha/IKK beta (Ser180/Ser181)  磷酸化KB抑制蛋白激酶α/β抗体

hz-3237R Phospho-IKK alpha/beta (Ser176/Ser180)  磷酸化KB抑制蛋白激酶α/β抗体

hz-2513R phospho-NFKBIA(Ser32/36)  磷酸化IKB alpha(Ser32/36)抗体

hz-3233R phospho-IKK beta(Tyr188)  磷酸化KB抑制蛋白激酶β抗体

hz-3231R phospho-IKK beta(Ser466)  磷酸化KB抑制蛋白激酶β抗体

hz-3232R phospho-IKK beta(Tyr199)  磷酸化KB抑制蛋白激酶β抗体

hz-5514R Phospho-NFKBIA (Tyr42)   磷酸化IKB α抗体

hz-5398R phospho-IKK beta(Ser471)  磷酸化KB抑制蛋白激酶β抗体

hz-5399R phospho-IKK beta(Ser740)  磷酸化KB抑制蛋白激酶β抗体

hz-5515R phospho-NFKBIA(Tyr305)  磷酸化IKB alpha抗体

hz-5440R phospho-IKK beta(Ser733)  磷酸化KB抑制蛋白激酶β抗体

hz-5441R phospho-IKK beta(S474)  磷酸化KB抑制蛋白激酶β抗体

hz-5442R phospho-IKK beta(Ser476)  磷酸化KB抑制蛋白激酶β抗体

hz-3227R phospho-IKK gamma (Ser85)  磷酸化KB抑制蛋白激酶γ抗体

hz-3228R phospho-IKK gamma (Ser31)  磷酸化KB抑制蛋白激酶γ抗体

hz-3230R phospho-IKK gamma (Ser376)  磷酸化KB抑制蛋白激酶γ抗体

hz-5393R phospho-IKK gamma(Ser43)  磷酸化KB抑制蛋白激酶γ抗体

hz-4114R IKBKE/IKKi  核因子κB抑制蛋白E抗体

hz-5454R phospho-IKBKE(Thr501)  磷酸化核因子κB抑制蛋白E抗体

hz-5517R phospho-NFKBIE (Ser157)  磷酸化KB抑制蛋白激酶ε

hz-0245R IKI3 family protein  拟南芥IKI3抗体

hz-2428R IL-9  白介素9抗体

hz-0698R IL-10  白细胞介素-10抗体

hz-1827R IL-11  白介素11抗体

hz-2459R IL-10RA  白细胞介素-10受体a抗体

hz-2602R IL-10RB/CRFB4  白细胞介素-10受体β抗体

hz-0767R IL-12  白介素12抗体