获取电话促进凋亡基因抗体
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
促进凋亡基因抗体产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）
促进凋亡基因抗体产品介绍
CIDE-B(DFF45)是凋亡信号通路中新近发现的促进凋亡的基因,在细胞凋亡中有重要的作用,有学者认为： CIDE-B在周围神经元损伤后,脊髓内CIDE-B即可表达增强,诱导神经元凋亡; 若阻断CIDE-B的表达,能有效抑制神经元的凋亡.cide-b在肿瘤方面研究也日趋增多，他的抑制可能与肿瘤的发生有关。
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as an inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE B induces apoptosis, which is inhibited by DFF45. CIDE B is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE B is expressed mainly in liver and small intestine and at lower levels in spleen, colon, kidney, peripheral blood lymphocytes, and bone marrow.
mol wt:24kDa
Other Aliases:
cell death activator CIDE-B; cell death-inducing DFFA-like effector B; Cide-b
xy-4083R phospho-c-Abl (Tyr134)磷酸化非受体酪氨酸激酶c-Abl抗体
xy-4084R phospho-c-Abl (Tyr253)磷酸化非受体酪氨酸激酶c-Abl抗体
xy-5149R CPI17 alpha蛋白磷酸激酶PKC/CPI-17抗体
xy-4085R phospho-c-Abl(Tyr272)磷酸化非受体酪氨酸激酶c-Abl抗体
xy-4086R phospho-c-Abl(Tyr276)磷酸化非受体酪氨酸激酶c-Abl抗体
xy-10088R CLPS胰辅脂酶抗体
促进凋亡基因抗体
xy-9681R C19orf4519号染色体开放阅读框45抗体
xy-9692R C20orf111过氧化氢诱导转录蛋白1抗体
xy-6202R CIKS核因子NFκB激活蛋白1抗体
xy-6987R C12orf23第12号染色体开放阅读框23抗体
xy-6990R γ-Cateninγ-连环素/连接蛋白γ抗体
xy-9767R C10orf410号染色体开放阅读框4抗体
xy-9768R C10orf4710号染色体开放阅读框47抗体
xy-9770R C10orf8110号染色体开放阅读框81抗体
xy-9683R C19orf4719号染色体开放阅读框47抗体
xy-9684R C19orf5419号染色体开放阅读框54抗体
xy-9685R C1GALT1N-乙酰半乳糖胺糖蛋白3、β-半乳糖转移酶1抗体
xy-9677R C19orf1819号染色体开放阅读框18抗体
xy-9678R C19orf2119号染色体开放阅读框21抗体
xy-9679R C19orf2419号染色体开放阅读框24抗体
xy-4851R Collagen alpha-1(II) chain Ⅱ型胶原α1蛋白/软骨钙素抗体
xy-11829R Cortexin 1皮质素1抗体
xy-9666R C8orf708号染色体开放阅读框70抗体
xy-6478R Carboxypeptidase H胰羧肽酶E抗体
xy-5405R phospho-CK18(Ser60)磷酸化细胞角蛋白18抗体
xy-9693R C20orf11220号染色体开放阅读框112抗体
xy-9771R C10orf8810号染色体开放阅读框88抗体
xy-9956R CRCT1富含半胱氨酸C端蛋白1抗体
xy-9957R CREG2E1A激活基因刺激蛋白2抗体
xy-9959R CWH43细胞壁合成蛋白43抗体
xy-9960R C19orf2919号染色体开放阅读框29抗体
xy-5274R phospho-CDKN1A (Ser130)磷酸化p21蛋白抗体