胞吐囊复合体蛋白2抗体

英文名称    EXOC2    

中文名称    胞吐囊复合体蛋白2抗体    

别    名    exocyst complex component 2; exocyst complex component Sec5; FLJ11026; SEC5; SEC5 like 1; SEC5L1; Sec5p; EXOC2_HUMAN.    

说 明 书    0.2ml      

研究领域    细胞生物  转录调节因子  转运蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 胞吐囊复合体蛋白2抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    104kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human EXOC2/SEC5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

胞吐囊复合体蛋白2抗体产品介绍    background:

The mammalian exocyst complex (sec 6/8) is a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Sec 5 is one of eight exocyst complex subunits: Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84. Exocyst complex regulation depends upon Sec5 binding Ral in a GTP-dependent manner. Human Sec5 maps to chromosome 6p25.3.

Function:
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. 

Subunit:
The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with EXOC3L1 (By similarity). Interacts with RALA and GNEFR/DELGEF. Interaction with GNEFR occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP. Interacts with RALB.

Subcellular Location:
Plasma membrane.

Tissue Specificity:
Widely expressed with highest levels in brain and placenta. 

Similarity:
Belongs to the SEC5 family. 
Contains 1 IPT/TIG domain. 

Database links:

Entrez Gene: 55770 Human

Entrez Gene: 66482 Mouse

Entrez Gene: 171455 Rat

SwissProt: Q96KP1 Human

SwissProt: Q9D4H1 Mouse

SwissProt: O54921 Rat

Unigene: 484412 Human

Unigene: 293510 Mouse

Unigene: 2869 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

胞吐囊复合体蛋白2抗体

hz-1755P EGFL7(EGF-like domain containing protein 7)  类表皮生长因子域7抗原

hz-1076P Egr-1(Early growth response 1)  早期反应基因-1/应急反应生长基因1抗原

hz-2446P phospho-eIF4E(pSer209)(phospho-Eukaryotic translation initiation factor 4E)  磷酸化eIF-4E（Ser209）抗原

hz-1398P ELK1  细胞转录因子ELK1抗原

hz-1756P Elastin  弹性蛋白抗原

hz-2651P ELAVL1/HuR peptide  ELAVL1/HuR多肽抗原

hz-0558P hzp1 (epithelial mhzbrane protein 1)  表皮膜蛋白1抗原

hz-1331P sFRP-4(Secreted frizzled-related protein 4; Frizzled protein, human endometrium)  抗子宫内膜抗原

hz-0547P Endostatin  内皮抑素/内皮他丁抗原

hz-1249P EpCAM(Epithelial cell adhesion molecule)  上皮细胞粘附分子/表皮细胞粘附分子（多肽）

hz-1513P EpCAM/CD326(Epithelial cell adhesion molecule)  上皮细胞粘附分子/表皮细胞粘附分子抗原

hz-0658P E.coli O6 (Escherichia coli O6)  E.coli O6大肠杆菌菌体蛋白

hz-2100P EPEC/E.coli(enteropathogenic E．coli，EPEC)  普通大肠埃希菌菌体蛋白（非致病性）

hz-1763P EphA1 R(Ephrin A1 Receptor)  EphA1-R受体抗原

hz-1424P EPOR peptide  红细胞生成素受体抗原

hz-1522P phospho-ERK1/MAPK-1/2(pThr183 + pTyr185)  磷酸化丝裂原活化蛋白激酶1/2抗原

hz-0996P ERK(Extracellular signal-regulated kinase)  丝裂原活化蛋白激酶抗原

hz-1020P MAPK1/ERK3 (Mitogen-activated protein kinase 3; P44MAPK)  丝裂原活化蛋白激酶3抗原

hz-1319P MAPK4(Mitogen-activated protein kinase 4)  丝裂原活化蛋白激酶4抗原

hz-0894P ER- Alpha(phospho-Ser167)peptide  人磷酸化雌激素受体α多肽抗原

hz-1643P ER- Alpha(phospho-Tyr537)peptide  磷酸化雌激素受体α抗原

hz-0253P ER- Alpha /ER alpha peptide  雌激素受体α抗原

hz-2098P ER- Alpha/ER alpha peptide  雌激素受体α抗原

hz-0255P ER- Beta (Estrogen receptor-beta) peptide  雌激素受体β抗原

hz-1285P ets1/E26 (E-twenty six 1)  Ets转录因子家族ets1抗原

hz-0852P EV71(Human enterovirus 71)VP1  肠道病毒71型/手足口病病毒抗原

hz-0983P EV71(Human enterovirus 71)VP1(CT)  肠道病毒71型/手足口病病毒抗原(C端)

hz-2221P ATEXPA10 peptide  植物扩张蛋白ATEXPA10（拟南芥）抗原

hz-1343P Ezrin/Radixin  埃兹蛋白（多肽）

hz-0949P F1 operon positive regulatory protein(NT)  鼠疫耶尔森氏菌F1荚膜蛋白(N端多肽）

hz-0950P F1 operon positive regulatory protein(CT)  鼠疫耶尔森氏菌F1荚膜蛋白(C端多肽）

hz-2135P FABP(brain) (Fatty acid-binding protein brain)  脑型脂肪酸结合蛋白抗原

hz-0511P FADD (Fas-associated protein with death domain)  Fas死亡结构域相关蛋白抗原

hz-1340P FAK(Focaladhesin kinase)  粘着斑激酶抗原