核苷转运蛋白ENT1抗体

英文名称    ENT1    

中文名称    核苷转运蛋白ENT1抗体    

别    名    Equilibrative NBMPR-sensitive nucleoside transporter; equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative nucleoside transporter 1; es-type; MGC1465; MGC3778; Nucleoside transporter; Nucleoside transporter, es-type; OTTHUMP00000016506; OTTHUMP00000016507; OTTHUMP00000016508; OTTHUMP00000016509; OTTHUMP00000016510; OTTHUMP00000016511; OTTHUMP00000016512; S29A1_HUMAN; SLC29A1; solute carrier family 29 (nucleoside transporters), member 1; Solute carrier family 29 member 1.    

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  信号转导  新陈代谢      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Cow, Horse, Sheep, Cynomolgus Monkey, Orangutan    

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 核苷转运蛋白ENT1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    50kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ENT1/SLC29A1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

核苷转运蛋白ENT1抗体产品介绍    background:

Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.

Function:
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).

Subcellular Location:
Basolateral cell membrane. Apical cell membrane. Predominantly localized in the basolateral membrane in polarised MDCK cells.

Tissue Specificity:
Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the SLC29A transporter family.    

核苷转运蛋白ENT1抗体

hz-0345R-FIThz Rabbit Anti-human IgM/FITC  FITC标记的兔抗人IgM

hz-0345R-hzy3 Rabbit Anti-human IgM/Cy3  Cy3标记的兔抗人IgM

hz-0345R-hzy5 Rabbit Anti-human IgM/Cy5  Cy5标记的兔抗人IgM

hz-0345R-hzy5.5 Rabbit Anti-human IgM/Cy5.5  Cy5.5标记的兔抗人IgM

hz-0345R-hzy7 Rabbit Anti-human IgM/Cy7  Cy7标记的兔抗人IgM

hz-0345R-PE Rabbit Anti-human IgM/PE  PE标记的兔抗人IgM

hz-0345R-PE-hzy3 Rabbit Anti-human IgM/PE-Cy3  PE-Cy3标记的兔抗人IgM

hz-0345R-PE-hzY5 Rabbit Anti-human IgM/PE-CY5  PE-CY5标记的兔抗人IgM

hz-0345R-APhz Rabbit Anti-human IgM/APC  APC标记的兔抗人IgM

hz-0345R-AF350 Rabbit Anti-human IgM/Alexa Fluor 350  Alexa Fluor 350标记的兔抗人IgM

hz-0345R-AF488 Rabbit Anti-human IgM/Alexa Fluor 488  Alexa Fluor 488标记的兔抗人IgM

hz-0345R-AF555 Rabbit Anti-human IgM/Alexa Fluor 555  Alexa Fluor 555标记的兔抗人IgM

hz-0345R-AF647 Rabbit Anti-human IgM/Alexa Fluor 647  Alexa Fluor 647标记的兔抗人IgM

hz-0345R-PE-hzy5.5 Rabbit Anti-human IgM/PE-Cy5.5  PE-Cy5.5标记的兔抗人IgM

hz-0345R-PE-hzy7 Rabbit Anti-human IgM/PE-Cy7  PE-Cy7标记的兔抗人IgM

hz-0345R-Gold Rabbit Anti-human IgM/Gold  胶体金标记的兔抗人IgM

hz-0345R-AP Rabbit Anti-human IgM/AP  碱性磷酸酶（AP）标记的兔抗人IgM

hz-0345R-RBIThz Rabbit Anti-human IgM/RBITC  罗丹明标记的兔抗人IgM

hz-0345R-Bio Rabbit Anti-human IgM/Bio  生物素标记的兔抗人IgM

hz-0345R-HRP Rabbit Anti-human IgM/HRP  辣根过氧化物酶标记的兔抗人IgM

hz-0360R-HRP Rabbit Anti-human sIgA/HRP  辣根过氧化物酶标记兔抗人IgA

hz-0360R-Bio Rabbit Anti-human sIgA/Bio  生物素标记的兔抗人分泌型IgA

hz-0360R-Gold Rabbit Anti-human sIgA/Gold  胶体金标记的兔抗人分泌型IgA

hz-0360R-hzy3 Rabbit Anti-human sIgA/Cy3  Cy3标记的兔抗人分泌型IgA

hz-0360R-hzy5 Rabbit Anti-human sIgA/Cy5  Cy5标记的兔抗人分泌型IgA

hz-0360R-hzy5.5 Rabbit Anti-human sIgA/Cy5.5  Cy5.5标记的兔抗人分泌型IgA

hz-0360R-hzy7 Rabbit Anti-human sIgA/Cy7  Cy7标记的兔抗人分泌型IgA

hz-0360R-PE Rabbit Anti-human sIgA/PE  PE标记的兔抗人分泌型IgA

hz-0360R-PE-hzy3 Rabbit Anti-human sIgA/PE-Cy3  PE-Cy3标记的兔抗人分泌型IgA

hz-0360R-PE-hzY5 Rabbit Anti-human sIgA/PE-CY5  PE-CY5标记的兔抗人分泌型IgA

hz-0360R-APhz Rabbit Anti-human sIgA/APC  APC标记的兔抗人分泌型IgA

hz-0360R-AF350 Rabbit Anti-human sIgA/Alexa Fluor 350  Alexa Fluor 350标记的兔抗人分泌型IgA

hz-0360R-AF488 Rabbit Anti-human sIgA/Alexa Fluor 488  Alexa Fluor 488标记的兔抗人分泌型IgA