真核翻译起始因子4B抗体

英文名称    EIF4B    

中文名称    真核翻译起始因子4B抗体    

别    名    EIF 4B; EIF-4B; Eukaryotic initiation factor 4B; IF4B_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  免疫学  细胞凋亡  转录调节因子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 真核翻译起始因子4B抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    69kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human EIF4B    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

真核翻译起始因子4B抗体产品介绍    background:

eIF4B is required for the binding of mRNA to ribosomes. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F。

Function:
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Subunit:
Self-associates and interacts with EIF3 p170 subunit. 

Post-translational modifications:
Phosphorylated at Ser-422 by RPS6KA1 and RPS6KB1; phosphorylation enhances the affinity of EIF4B for the EIF3 complex. 

Similarity:
Contains 1 RRM (RNA recognition motif) domain. 

Database links:
UniProtKB/Swiss-Prot: P23588.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

真核翻译起始因子4B抗体

HZH586Hu 人肌纤蛋白(MYOC)ELISA试剂盒 ELISA Kit for Myocilin (MYOC) 

HZF368Hu 人肉毒碱棕榈酰基转移酶1A(CPT1A)ELISA试剂盒 ELISA Kit for Carnitine Palmitoyltransferase 1A, Liver (CPT1A) 

HZB000Hu 人白细胞关联免疫球蛋白样受体2(LAIR2)ELISA试剂盒 ELISA Kit for Leukocyte Associated Immunoglobulin Like Receptor 2 (LAIR2) 

HZB134Hu 人黑色素瘤关联硫酸软骨素蛋白聚糖(MCSP)ELISA试剂盒 ELISA Kit for Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP) 

HZC419Hu 人Catheli抗菌肽(CAMP)ELISA试剂盒 ELISA Kit for Cathelicidin Antimicrobial Peptide (CAMP) 

HZC228Hu 人密封蛋白(OCLN)ELISA试剂盒 ELISA Kit for Occludin (OCLN) 

HZC388Hu 人封闭蛋白1(CLDN1)ELISA试剂盒 ELISA Kit for Claudin 1 (CLDN1) 

HZF294Hu 人封闭蛋白4(CLDN4)ELISA试剂盒 ELISA Kit for Claudin 4 (CLDN4) 

HZC596Hu 人血管活性肠肽受体1(VIPR1)ELISA试剂盒 ELISA Kit for Vasoactive Intestinal Peptide Receptor 1 (VIPR1) 

HZA514Hu 人失调蛋白1(ATXN1)ELISA试剂盒 ELISA Kit for Ataxin 1 (ATXN1) 

HZC150Hu 人Ⅵ型胶原α1(COL6α1)ELISA试剂盒 ELISA Kit for Collagen Type VI Alpha 1 (COL6a1) 

HZC300Hu 人中脑星形胶质细胞来源神经营养因子(MANF)ELISA试剂盒 ELISA Kit for Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF) 

HZC511Hu 人酸性葡萄糖苷酶β(GβA)ELISA试剂盒 ELISA Kit for Glucosidase Beta, Acid (GbA) 

HZD879Hu 人Syncollin蛋白(SYCN)ELISA试剂盒 ELISA Kit for Syncollin (SYCN) 

HZB251Hu 人肿瘤坏死因子配体超家族成员7(TNFSF7)ELISA试剂盒 ELISA Kit for Tumor Necrosis Factor Ligand Superfamily, Member 7 (TNFSF7) 

HZB794Hu 人成纤维细胞生长因子受体2(FGFR2)ELISA试剂盒 ELISA Kit for Fibroblast Growth Factor Receptor 2 (FGFR2) 

HZH615Hu 人间皮素(MSLN)ELISA试剂盒 ELISA Kit for Mesothelin (MSLN) 

HZC513Hu 人颗粒体蛋白(GRN)ELISA试剂盒 ELISA Kit for Granulin (GRN) 

HZG677Hu 人视锥蛋白样蛋白1(VSNL1)ELISA试剂盒 ELISA Kit for Visinin Like Protein 1 (VSNL1) 

HZC869Hu 人丝甘蛋白聚糖(SRGN)ELISA试剂盒 ELISA Kit for Serglycin (SRGN) 

HZC146Hu 人Ⅷ型胶原α1(COL8α1)ELISA试剂盒 ELISA Kit for Collagen Type VIII Alpha 1 (COL8a1) 

HZC537Hu 人低氧上调节因子1(HYOU1)ELISA试剂盒 ELISA Kit for Hypoxia Up Regulated 1 (HYOU1) 

HZH776Hu 人中间α-球蛋白抑制因子H4(ITIH4)ELISA试剂盒 ELISA Kit for Inter Alpha-Globulin Inhibitor H4 (ITIH4) 

HZC321Hu 人无孢蛋白(ASPN)ELISA试剂盒 ELISA Kit for Asporin (ASPN) 

HZH337Hu 人过氧化物酶体增殖物激活受体γ辅激活因子1α(PPARγC1α)ELISA试剂盒 ELISA Kit for Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) 

HZC128Hu 人Gremlin 1蛋白(GREM1)ELISA试剂盒 ELISA Kit for Gremlin 1 (GREM1)