获取电话英文名称 Phospho-EEF2 (Thr57)
中文名称 磷酸化真核翻译延长因子2抗体
别 名 EEF2 (phospho T57); p-EEF2 (phospho T57); EEF2; EF2; Elongation factor 2; Eukaryotic translation elongation factor 2; Eukaryotic Elongation Factor-2; EF2_HUMAN; EF-2.
说 明 书 0.1ml
产品类型 磷酸化抗体
研究领域 肿瘤 细胞生物 免疫学 信号转导 细胞凋亡 转录调节因子 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 磷酸化真核翻译延长因子2抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human EEF2 around the phosphorylation site of Thr56
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
磷酸化真核翻译延长因子2抗体产品介绍 background:
EEF2 is a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation.
Function:
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
Subcellular Location:
Cytoplasm.
Post-translational modifications:
Phosphorylation by EF-2 kinase completely inactivates EF-2.
Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A, thus arresting protein synthesis.
ISGylated.
Similarity:
Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
Database links:
UniProtKB/Swiss-Prot: P13639.4
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化真核翻译延长因子2抗体
HZA930Hu 人细胞外信号调节激酶2(ERK2)ELISA试剂盒 ELISA Kit for Extracellular Signal Regulated Kinase 2 (ERK2)
HZA212Hu 人基质金属蛋白酶23B(MMP23B)ELISA试剂盒 ELISA Kit for Matrix Metalloproteinase 23B (MMP23B)
HZB471Hu 人间隙连接蛋白26(CX26)ELISA试剂盒 ELISA Kit for Connexin 26 (CX26)
HZB472Hu 人碱性磷酸酶(ALP)ELISA试剂盒 ELISA Kit for Alkaline Phosphatase (ALP)
HZB477Hu 人基质Gla蛋白(MGP)ELISA试剂盒 ELISA Kit for Matrix Gla Protein (MGP)
HZB479Hu 人肝素结合性表皮生长因子(HBEGF)ELISA试剂盒 ELISA Kit for Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)
CEA991Hu 人饥饿素(GHRL)ELISA试剂盒 ELISA Kit for Ghrelin (GHRL)
CEA708Hu 人δ-促睡眠肽(δSIP)ELISA试剂盒 ELISA Kit for Delta-Sleep Inducing Peptide (dSIP)
HZA709Hu 人Toll样受体9(TLR9)ELISA试剂盒 ELISA Kit for Toll Like Receptor 9 (TLR9)
HZA223Hu 人白介素1受体拮抗剂(IL1RA)ELISA试剂盒 ELISA Kit for Interleukin 1 Receptor Antagonist (IL1RA)
HZA945Hu 人趋化素(CHEM)ELISA试剂盒 ELISA Kit for Chemerin (CHEM)
HZA960Hu 人ATP结合盒转运蛋白G2(ABCG2)ELISA试剂盒 ELISA Kit for ATP Binding Cassette Transporter G2 (ABCG2)
HZA973Hu 人血管紧张素Ⅱ受体2(AGTR2)ELISA试剂盒 ELISA Kit for Angiotensin II Receptor 2 (AGTR2)
AEA044Hu 人抗生长激素抗体(Anti-GHAb)ELISA试剂盒 ELISA Kit for Anti-Growth Hormone Antibody (Anti-GHAb)
AEA895Hu 人抗胰岛素受体抗体(AIRA)ELISA试剂盒 ELISA Kit for Anti-Insulin Receptor Antibody (AIRA)
HZA512Hu 人纤维介素蛋白(FGL2)ELISA试剂盒 ELISA Kit for Fibrinogen Like Protein 2 (FGL2)
HZA519Hu 人载脂蛋白A1(APOA1)ELISA试剂盒 ELISA Kit for Apolipoprotein A1 (APOA1)
HZA520Hu 人蛋白激酶R(PKR)ELISA试剂盒 ELISA Kit for Protein Kinase R (PKR)
HZA536Hu 人亮氨酰氨基肽酶(LAP)ELISA试剂盒 ELISA Kit for Leucine Aminopeptidase (LAP)
HZA565Hu 人硫酸肝素蛋白聚糖(HSPG)ELISA试剂盒 ELISA Kit for Heparan Sulfate Proteoglycan (HSPG)
HZA649Hu 人硫酸皮肤素(DS)ELISA试剂盒 ELISA Kit for Dermatan Sulfate (DS)
HZA723Hu 人硫酸软骨素(CS)ELISA试剂盒 ELISA Kit for Chondroitin Sulfate (CS)
HZA724Hu 人前列腺素D2合成酶(PGD2S)ELISA试剂盒 ELISA Kit for Prostaglandin D2 Synthase, Brain (PGD2S)
HZA725Hu 人葡萄糖6磷酸异构酶(GPI)ELISA试剂盒 ELISA Kit for Glucose 6 Phosphate Isomerase (GPI)
HZA726Hu 人转甲状腺素蛋白(TTR)ELISA试剂盒 ELISA Kit for Transthyretin (TTR)
CEA727Ge 人前列环素(PGI2)ELISA试剂盒 ELISA Kit for Prostacyclin (PGI2)
HZA729Hu 人桥粒芯糖蛋白1(DSG1)ELISA试剂盒 ELISA Kit for Desmoglein 1 (DSG1)
HZA805Hu 人鞘磷脂(SPH)ELISA试剂盒 ELISA Kit for Sphingomyelin (SPH)
CEA996Hu 人胎儿血红蛋白(HBF)ELISA试剂盒 ELISA Kit for Fetal Hemoglobin (HBF)
HZA998Hu 人磷脂酰肌醇蛋白聚糖4(GPC4)ELISA试剂盒 ELISA Kit for Glypican 4 (GPC4)
HZB214Hu 人天冬氨酸转氨酶(AST)ELISA试剂盒 ELISA Kit for Aspartate Aminotransferase (AST)
