英文名称 eEF1A1
中文名称 翻译延伸因子EF-1a抗体
别 名 Elongation Factor 1, Alpha; EF1 Alpha; eukaryotic translation elongation factor 1 alpha 1; CCS3; eEF1A-1; EF-Tu; EF1A; Elongation factor Tu; GRAF-1EF; PTI1; elongation factor 1-alpha 1; EEF-1; EEF1A; Eef1a2; Eef1a2l1; EF1A; MGC125172; SI; Eef1a1; EF1A1_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 细胞生物 免疫学 信号转导 细胞凋亡 转录调节因子 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 翻译延伸因子EF-1a抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human EF1 alpha
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
翻译延伸因子EF-1a抗体产品介绍 background:
eEF1A1 is an isoform of the alpha subunit of the elongation factor 1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. It promotes the GTP dependent binding of aminoacyl tRNA to the A site of ribosomes during protein biosynthesis. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome (referenced from entrez gene and swissprot).
Function:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle
Post-translational modifications:
ISGylated.
Similarity:
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.
Gene ID:
1915
Database links:
Entrez Gene: 1915 Human
Entrez Gene: 13627 Mouse
Entrez Gene: 171361 Rat
Omim: 130590 Human
SwissProt: P68104 Human
SwissProt: P10126 Mouse
SwissProt: P62630 Rat
Unigene: 520703 Human
Unigene: 535192 Human
Unigene: 586423 Human
Unigene: 695681 Human
Unigene: 713109 Human
Unigene: 138471 Mouse
Unigene: 335315 Mouse
Unigene: 360075 Mouse
Unigene: 391071 Mouse
Unigene: 468942 Mouse
Unigene: 144660 Rat
Unigene: 965 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
翻译延伸因子EF-1a抗体
hz-1023R CSF3/G-CSF 粒细胞-巨噬细胞集落刺激因子3抗体
hz-5116R GDIA1 肿瘤转移抑制基因GDIA1抗体
hz-5126R GDIA2/ARHGDIB 肿瘤转移抑制基因GDIA2抗体
hz-2574R G-CSFR/CD114 粒细胞-巨噬细胞集落刺激因子3受体抗体
hz-2356R GKRP 葡萄糖激酶调节蛋白抗体
hz-1794R GDF-1 生长、分化因子1抗体
hz-5099R GDF3 生长分化因子3抗体
hz-1288R GDF8/MSTN 生长分化因子8抗体
hz-2227G GDF8 生长分化因子8/肌肉抑制素抗体
hz-1795R GDF9 生长分化因子9抗体
hz-3818R GDF15/MIC-1 生长分化因子15/巨嗜细胞抑制因子1抗体
hz-1024R GDNF 胶质细胞源性神经营养因子抗体
hz-5972R Ribonuclease 6 核糖核酸酶6抗体
hz-5973R SIRT7 沉默调节样蛋白SirT7抗体
hz-1160R Gelsolin 凝溶胶蛋白抗体
hz-4292R BPI 杀菌/通透性增强蛋白抗体
hz-0199R GFAP 胶质纤维酸性蛋白抗体
hz-5355R phospho-GFAP (Ser8) 磷酸化胶质纤维酸性蛋白抗体
hz-6193R SMYD2 组蛋白甲基转移酶SMYD2抗体
hz-5974R SMYD3 组蛋白甲基转移酶SMYD3抗体
hz-6108R SMYD4 组蛋白甲基转移酶SMYD4抗体
hz-5975R SSX8 滑膜肉瘤X断点蛋白8抗体
hz-0639R GFP 绿色荧光蛋白(免疫组化用抗体)
hz-0844R GFP 绿色荧光蛋白抗体
hz-0890R GFP 绿色荧光蛋白抗体
hz-2194R EGFP 重组增强型绿色荧光蛋白抗体
hz-5977R c-Maf 原癌基因cMAF抗体
hz-5976R c-Maf 原癌基因cMAF抗体
hz-5978R c-Myb 转录激活因子MYB抗体
hz-0168R GFRA4 GDNF家族受体α-4抗体
hz-0201R GFR Alpha-1 GDNF家族受体α-1抗体
hz-0654R GHR 生长激素受体抗体
hz-5979R l-Myc Myc基因肺癌相关蛋白抗体