磷酸化多巴胺转运蛋白DAT抗体

英文名称    phospho-Dopamine Transporter (Thr53)    

中文名称    磷酸化多巴胺转运蛋白DAT抗体    

别    名    Dopamine Transporter (phospho T53); p-Dopamine Transporter (phospho T53); p-DAT1(phospho T53); DA transporter; DAT 1; DAT; SC6A3_RAT; DAT1; Dopamine transporter 1; Dopamine transporter; PKDYS; SC6A3_HUMAN; SLC6A3; Sodium dependent dopamine transporter; Sodium-dependent dopamine transporter; Solute carrier family 6 (neurotransmitter transporter dopamine), member 3; Solute carrier family 6 (neurotransmitter transporter), member 3; Solute carrier family 6 member 3; Variable number tandem repeat (VNTR).    

说 明 书    0.1ml      

产品类型    磷酸化抗体     

研究领域    细胞生物  神经生物学  结合蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Mouse, Rat, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 磷酸化多巴胺转运蛋白DAT抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    69kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from human Dopamine Transporter around the phosphorylation site of Thr53    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化多巴胺转运蛋白DAT抗体产品介绍    background:

This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]

Function:
Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.

Subcellular Location:
Membrane.

DISEASE:
Defects in SLC6A3 are the cause of dystonia-parkinsonism infantile (DYTPRI) [MIM:613135]. It is a neurodegenerative disorder characterized by infantile onset of parkinsonism and dystonia. Other neurologic features include global developmental delay, bradikinesia and pyramidal tract signs.

Similarity:
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.

Gene ID:
24898

Database links:

Entrez Gene: 24898 Rat

SwissProt: P23977 Rat

Unigene: 10093 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

磷酸化多巴胺转运蛋白DAT抗体

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hz-5151R Acrosin  精子顶体前体蛋白抗体

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hz-0007R ADM/AM/Adrenomedullin  肾上腺髓质素抗体

hz-0995R ADM (ProAM-N20)  肾上腺髓质素抗体(N端20肽)

hz-0090R ADM R  肾上腺髓质素受体抗体

hz-5147R C CBL  原癌基因CBL2抗体

hz-5328R 5HT3C/5HT3E   5-羟色胺受体3C抗体

hz-4071R phospho-C CBL(Tyr674)  磷酸化原癌基因CBL2抗体

hz-0039R ADNP/NAP  活性依赖的神经保护肽抗体

hz-4072R Cphospho-C CBL(Tyr700)  磷酸化原癌基因CBL2抗体

hz-1225R ADORA3  腺苷受体A3抗体

hz-2640R ADO  2-氨基乙硫醇双加氧酶抗体

hz-2203R Integrin Alpha V  整合素αV抗体

hz-5149R CPI17 alpha  蛋白磷酸激酶PKC/CPI-17抗体

hz-4073R phospho-CPI17 alpha (Thr38)   磷酸化蛋白磷酸激酶PKC/CPI-17抗体

hz-1062R ADRA2  ADRA2肾上腺素能受体2抗体

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hz-5150R APE/Girdin  肌动蛋白结合蛋白Girdin抗体

hz-5835R Drebrin  脑发育调节蛋白抗体

hz-5152R DAG1  肌萎缩相关蛋白DAG1抗体

hz-0947R ADRB2  肾上腺素能受体β2抗体（β2-AR ）

hz-3002R phospho-ADRB2(Ser346)  磷酸化肾上腺素能受体β2抗体

hz-5211R phospho-ADRB2 (Ser261)  磷酸化肾上腺素能受体β2抗体