获取电话英文名称 DNAH2
中文名称 轴丝动力蛋白2抗体
别 名 axonemal; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dnah2; DYH2_HUMAN; Dynein heavy chain 2; Dynein heavy chain domain-containing protein 3.
说 明 书 0.2ml
研究领域 细胞生物 信号转导 细胞骨架
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Horse,
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 轴丝动力蛋白2抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 507kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNAH2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
轴丝动力蛋白2抗体产品介绍 background:
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]
Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.
Subcellular Location:
Cytoplasm; cytoskeleton; cilium axoneme.
Tissue Specificity:
Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in lung.
Similarity:
Belongs to the dynein heavy chain family.
Contains 5 TPR repeats.
Gene ID:
146754
Database links:
Entrez Gene: 146754 Human
SwissProt: Q9P225 Human
Unigene: 367649 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
轴丝动力蛋白2抗体
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