磷酸化金属离子转运体1抗体

英文名称    phospho-Dematin (Ser403)    

中文名称    磷酸化金属离子转运体1抗体    

别    名    Dematin (phospho S403); P-Dematin (phospho S403); DCT 1; DCT1; Divalent metal transporter 1; DMT 1; Natural resistance associated macrophage protein 2; NRAMP 2; NRAMP2; DEMA_HUMAN.    

说 明 书    0.2ml      

产品类型    磷酸化抗体     

研究领域    细胞生物  信号转导  结合蛋白  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 磷酸化金属离子转运体1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    45kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from human Dematin around the phosphorylation site of Ser403    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化金属离子转运体1抗体产品介绍    background:

Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).[supplied by OMIM, Apr 2009]

Function:
Actin-bundling protein. May function in mitogen-activated protein kinase pathway.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Heart, brain, lung, skeletal muscle, and kidney.

Post-translational modifications:
Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase.
The N-terminus is blocked.

Similarity:
Belongs to the villin/gelsolin family.
Contains 1 HP (headpiece) domain.

Gene ID:
2039

Database links:

Entrez Gene: 2039 Human

Entrez Gene: 13829 Mouse

Entrez Gene: 361069 Rat

Omim: 125305 Human

SwissProt: Q08495 Human

SwissProt: Q9WV69 Mouse

Unigene: 106124 Human

Unigene: 210863 Mouse

Unigene: 446654 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

磷酸化金属离子转运体1抗体

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hz-1046P MIP-1 Beta (macrophage inflammatory protein 1 Beta)  巨噬细胞炎症因子1β 抗原

hz-1959P CD122/IL-2RB(Imterleukm-2 Receptor beta)  CD122/白介素2受体β链抗原

hz-1162P MIP2 (myocardial ischhzic preconditioning upregulated protein 2)  巨噬细胞炎症蛋白2抗原

hz-0575P MMP-13 (Matrix metalloproteinase 13)  基质金属蛋白酶13抗原

hz-0985P MMP-20(matrix metalloproteinase 20)  基质金属蛋白酶20抗原

hz-1862P MMP-17(Matrix metalloproteinase-17)  基质金属蛋白酶-17抗原

hz-1377P MMP-26(Matrix metalloproteinase-26)  基质金属蛋白酶-26抗原

hz-2099P MMP-9(matrix metalloproteinase 9)  基质金属蛋白酶-9抗原

hz-1344P MMP-10(matrix metalloproteinase 10)  基质金属蛋白酶-10抗原

hz-1061P MPO peptide  髓过氧化物酶抗原

hz-1092P MRP2 (multidrug resistance-associated protein2)  多药耐药相关蛋白2

hz-1437P MRP5/ABCC5(Multidrug Resistanec-Associated Protein 5)  多药耐药相关蛋白5抗原

hz-0818P MrpL28 (mitochondrial ribosomal protein L28)  线粒体核糖体蛋白L28(抗原)

hz-0836P MLH1(Mutl homolog l gene)  错配修复蛋白1抗原

hz-1022P MUC5AC/Mucin 5AC(Gastric Mucin M1)  胃粘液素抗原

hz-0963P MTNR1B/MTNR-1B(Melatonin receptor 1B)  褪黑素受体1B抗原

hz-1445P MLN(Motilin)peptide  胃动素多肽

hz-1992P mTOR(Mammalian target of rapamycin)  雷帕霉素靶蛋白

hz-1018P Muc-1/CD227  粘蛋白-1/上皮膜

hz-1047P MyD88 (myeloid differential protein-88)  髓样分化蛋白抗原

hz-2032P PMP2/FABP8(peripheral myelin protein 2)  周围神经髓鞘蛋白2抗原

hz-2166P MYSM1(Myb-like, SWIRM and MPN domain-containing protein 1)  MYSM1抗原

hz-1267P MYOZ/MYOZ1(Myozenin)human、ret、mouse  MYOZ抗原

hz-1049P CHRNA7(Nicotinic-Acetylcholine receptor alpha 7)  烟碱型乙酰胆碱受体α7(多肽)

hz-0829P Nanog fragment  干细胞关键蛋白(多肽)

hz-0903P Natrexone/BSA:Natrexone/KLH  纳曲酮偶联牛血清白蛋白：纳曲酮偶联血蓝蛋白

hz-1052P NAP1 (nucleosome asshzbly protein 1)  核小体组装蛋白1（多肽）

hz-1172P N-cadherin  N-钙粘附分子抗原

hz-1519P E-cadherin  E-钙粘附分子抗原

hz-0513P Nephrin Protein  去氧肾上腺素

hz-1055P Neurocan  神经粘蛋白抗原

hz-1366P NF2/merlin(neurofibromatosis type 2)  2型神经纤维瘤抗原

hz-1417P NFATc1  活化T细胞核因子1蛋白